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一名感染艾滋病毒的人二期梅毒复发——一种新情况。

Relapse of secondary syphilis in a PLHIV - A new entity.

作者信息

Sankaranantham Murugan

机构信息

Department of Dermatology, Venereology and Leprosy, Sree Mookambika Medical College, Kanniyakumari, Tamil Nadu, India.

出版信息

Indian J Sex Transm Dis AIDS. 2024 Jul-Dec;45(2):147-149. doi: 10.4103/ijstd.ijstd_24_24. Epub 2024 Dec 13.

DOI:10.4103/ijstd.ijstd_24_24
PMID:39886237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11776901/
Abstract

Syphilis and other bacterial sexually transmitted infections (STIs) are on the verge of resurge throughout the world. Coinfection of syphilis and HIV is quite common as they both share a common mode of transmission. The behavior of syphilis is quite altered in the presence of HIV. Relapse of secondary syphilis after the recommended treatment is quite unusual. One such case has been reported, and possible pathogenesis was discussed.

摘要

梅毒和其他细菌性性传播感染在全球范围内正处于再度流行的边缘。梅毒和艾滋病毒的合并感染相当常见,因为它们有着共同的传播途径。在感染艾滋病毒的情况下,梅毒的表现会有很大变化。推荐治疗后二期梅毒复发的情况相当罕见。本文报告了这样一个病例,并讨论了可能的发病机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ff/11776901/2e63bbf04e0b/IJSTD-45-147-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ff/11776901/63a49a42d708/IJSTD-45-147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ff/11776901/2e63bbf04e0b/IJSTD-45-147-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ff/11776901/63a49a42d708/IJSTD-45-147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6ff/11776901/2e63bbf04e0b/IJSTD-45-147-g002.jpg

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本文引用的文献

1
The profile of sexually transmitted infections of men who have sex with men: A tertiary care center-based comparative cross-sectional study.男男性行为者性传播感染情况:一项基于三级医疗中心的比较横断面研究。
Indian J Sex Transm Dis AIDS. 2023 Jul-Dec;44(2):128-131. doi: 10.4103/ijstd.ijstd_14_21. Epub 2023 Dec 6.
2
Prevalence of syphilis among people living with HIV and its implication for enhanced coinfection monitoring and management in China: A meta-analysis.梅毒在 HIV 感染者中的流行情况及其对加强中国合并感染监测和管理的意义:一项荟萃分析。
Front Public Health. 2022 Oct 17;10:1002342. doi: 10.3389/fpubh.2022.1002342. eCollection 2022.
3
Sexually Transmitted Infections Treatment Guidelines, 2021.
《2021年性传播感染治疗指南》
MMWR Recomm Rep. 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1.
4
Factors associated with syphilis treatment failure and reinfection: a longitudinal cohort study in Shenzhen, China.梅毒治疗失败和再感染的相关因素:中国深圳的一项纵向队列研究
BMC Infect Dis. 2017 Sep 13;17(1):620. doi: 10.1186/s12879-017-2715-z.
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Factors determining serologic response to treatment in patients with syphilis.影响梅毒患者治疗后血清学应答的因素。
Clin Infect Dis. 2009 Nov 15;49(10):1505-11. doi: 10.1086/644618.
6
Syphilis and HIV: a dangerous combination.梅毒与艾滋病毒:危险的组合。
Lancet Infect Dis. 2004 Jul;4(7):456-66. doi: 10.1016/S1473-3099(04)01061-8.
7
Syphilis and human immunodeficiency virus co-infection.梅毒与人类免疫缺陷病毒合并感染。
J Natl Med Assoc. 2003 May;95(5):363-82.