钆塞酸二钠增强肝胆期磁共振成像的细胞内增强技术：肝功能评估
Intracellular enhancement technique for gadoxetic acid-enhanced hepatobiliary-phase magnetic resonance imaging: evaluation of hepatic function.
作者信息
Fonseca Dara, Nakamura Yuko, Higaki Toru, Maeda Shogo, Nishihara Takashi, Bito Yoshitaka, Takizawa Masahiro, Kondo Shota, Higashino Ryo, Morishita Shintaro, Akiyama Yuji, Fukuma Shingo, Kawaoka Tomokazu, Tsuge Masataka, Oka Shiro, Awai Kazuo
机构信息
Hiroshima University, Hiroshima City, Japan.
FUJIFILM Corporation, Shintoyofuta, Kashiwa City, Japan.
出版信息
Abdom Radiol (NY). 2025 Jan 31. doi: 10.1007/s00261-025-04817-y.
PURPOSE
To investigate the utility of intracellular enhancement (ICE) technique which suppresses signals from the extracellular space for the evaluation of hepatic function on gadoxetic acid-enhanced hepatobiliary-phase (HBP) images.
METHODS
We subjected 67 patients with suspected neoplastic hepatic lesions to gadoxetic acid-enhanced HBP imaging with and without ICE [i-HBP, conventional-HBP (c-HBP)]. A radiologist calculated the liver/spleen contrast (LSC) [LSC = signal intensity (SI) of liver/SI of spleen]. Receiver-operating analysis was used to evaluate the diagnostic value of the LSC on i-HBP- (i-LSC) and c-HBP images (c-LSC) to differentiate between Child-Pugh classes A and B.
RESULTS
Of the 67 patients, 57 were in Child-Pugh class A and 10 were in class B. For their differentiation, the area under the curve value of i-LSC was higher than of c-LSC (0.81 vs. 0.68).
CONCLUSIONS
ICE technique can improve the accuracy of estimating hepatic function on HBP images.
目的
研究细胞内增强（ICE）技术在钆塞酸增强肝胆期（HBP）图像上评估肝功能的效用，该技术可抑制细胞外间隙的信号。
方法
我们对67例疑似肝脏肿瘤性病变的患者进行了钆塞酸增强的HBP成像，包括有ICE [i-HBP，传统HBP（c-HBP）]和无ICE的情况。一名放射科医生计算肝脏/脾脏对比度（LSC）[LSC =肝脏信号强度（SI）/脾脏SI]。采用受试者操作分析来评估i-HBP图像（i-LSC）和c-HBP图像（c-LSC）上LSC区分Child-Pugh A级和B级的诊断价值。
结果
67例患者中，57例为Child-Pugh A级，10例为B级。对于两者的区分，i-LSC的曲线下面积值高于c-LSC（0.81对0.68）。
结论
ICE技术可提高HBP图像上肝功能评估的准确性。
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