Song Li-Ling, Peel Alica J, Veale David, Eley Thalia C, Krebs Georgina
Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
J Affect Disord. 2025 May 1;376:206-215. doi: 10.1016/j.jad.2025.01.146. Epub 2025 Jan 29.
BDD and OCD symptoms often co-occur, but the associations between specific symptoms remain unclear. Furthermore, current research suggests that the clinical presentation of emotional disorders can differ in individuals who self-report exposure to trauma, but it is unclear whether this extends to BDD and OCD. The current study aimed to: (a) investigate associations between individual OCD and BDD symptoms and (b) determine whether symptom networks differ in those with self-reported trauma compared to those without self-reported trauma.
Participants (N = 3127) were drawn from the Genetic Links to Anxiety and Depression (GLAD) Study and had completed validated self-reported questionnaires to assess BDD and OCD symptoms, and childhood and adulthood experiences of trauma. Network analysis was used to investigate associations between seven BDD symptoms and six OCD symptom domains. Networks of reporters and non-reporters of lifetime trauma were compared using the network comparison test.
BDD and OCD symptoms clustered distinctively with some bridging associations between them. The strongest bridging edges highlighted an association between three core BDD symptoms and the OCD domain of obsessional thoughts. BDD and OCD networks of reporters and non-reporters of lifetime trauma did not differ.
Cross-sectional design, meaning causality cannot be inferred.
The findings suggest that BDD and OCD symptoms cluster distinctively, with some bridging associations between core BDD symptoms and obsessional thoughts. Future research is needed to understand the mechanisms underpinning this relationship.
躯体变形障碍（BDD）和强迫症（OCD）症状常同时出现，但特定症状之间的关联尚不清楚。此外，当前研究表明，自我报告有创伤经历的个体，其情绪障碍的临床表现可能有所不同，但尚不清楚这是否也适用于BDD和OCD。本研究旨在：（a）调查个体强迫症和躯体变形障碍症状之间的关联，以及（b）确定自我报告有创伤经历者与无创伤经历者的症状网络是否存在差异。
参与者（N = 3127）来自焦虑与抑郁的遗传联系（GLAD）研究，他们完成了经过验证的自我报告问卷，以评估BDD和OCD症状，以及童年和成年期的创伤经历。采用网络分析来研究七种BDD症状与六个OCD症状领域之间的关联。使用网络比较测试比较有终身创伤经历者和无终身创伤经历者的症状网络。
BDD和OCD症状明显聚类，且它们之间存在一些桥接关联。最强的桥接边突出显示了三种核心BDD症状与强迫观念的OCD领域之间的关联。有终身创伤经历者和无终身创伤经历者的BDD和OCD症状网络没有差异。
横断面设计，这意味着无法推断因果关系。
研究结果表明，BDD和OCD症状明显聚类，核心BDD症状与强迫观念之间存在一些桥接关联。未来需要开展研究以了解这种关系背后的机制。
