Gur D, Good W F, Herbert D L, Yonas H, Wozney P, Van Thiel D H, Wolfson S K
J Comput Assist Tomogr. 1985 May-Jun;9(3):447-50. doi: 10.1097/00004728-198505000-00004.
In the noninvasive, nonradioactive xenon/CT method of blood flow measurement, xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT; time-dependent xenon concentration within various tissue segments is then used to derive local blood flow maps. The usefulness of the method in the assessment of local cerebral blood flow has been documented. In this paper we explore its application to blood flow measurement in the human liver. In our preliminary clinical studies, hepatic blood flow ranged from 50 to 120 ml/100 cc/min in normal and adequately supplied tissue, and lower flow values were observed in tissue with abnormal function. The advantages and limitations of the method in such applications are discussed.
在无创、非放射性的氙/CT血流测量方法中，吸入氙气，通过连续CT测量吸入产生的放射影像学增强的时间变化；然后利用不同组织段内随时间变化的氙浓度来得出局部血流图。该方法在评估局部脑血流方面的实用性已有文献记载。在本文中，我们探讨其在人体肝脏血流测量中的应用。在我们的初步临床研究中，正常且血供充足的组织中肝血流范围为50至120毫升/100立方厘米/分钟，而在功能异常的组织中观察到较低的血流值。本文讨论了该方法在此类应用中的优缺点。
