Ebrahimi Pouyan, Ghezel Mohammad-Amin, Hosseini-Berneti Seyed-Hossein, Lashkarbolouki Amir-Hossein, Karami Mohsen, Nikbakht Hossein-Ali
Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Department of Parasitology and Mycology, Babol University of Medical Sciences, Babol, Iran.
Arch Iran Med. 2024 Dec 1;27(12):654-659. doi: 10.34172/aim.31147.
Blood cancers account for a significant proportion of cancer-related deaths worldwide. In this study, hematological cancer mortality in northern Iran was examined during 2013-2021, along with age-adjusted mortality rates.
In a cross-sectional study, we conducted an analysis of all deaths from hematological neoplasms registered in Babol city between 2013 and 2021. In order to estimate the population, the most recent census data was used. The mortality rates and trends for each hematological malignancy were reported in crude mortality rate (CMR) and age-standardized mortality rate (ASMR).
In total, 357 deaths (10.8% of all cancer-related deaths) were attributed to hematological neoplasms, with an average age of 61.9±19.3 years. The crude and age-adjusted mortality rates of hematological neoplasms increased from 3.1 and 2.7 per 100000 people in 2013 to 8.1 and 6.9 per 100,000 people in 2021, respectively. Mortality trends of hematological cancers increased with age decade for both sexes (<0.001). Additionally, when examining the trends of each hematological neoplasm, there was a significant increase in neoplasms including non-Hodgkin lymphoma (=0.033), multiple myeloma (=0.002), and leukemia (<0.001), except for the consistent trend observed in Hodgkin lymphoma (=0.247).
The trend of hematological malignancies in Babol city is increasing across all age groups and in both sexes. This study emphasizes the need for effective prevention and treatment strategies, including improving access to cancer care, enhancing surveillance in families with blood malignancies and reducing modifiable risk factors. Additionally, further research is warranted to develop targeted interventions.
血癌在全球癌症相关死亡中占相当大的比例。在本研究中，对2013 - 2021年伊朗北部的血液系统癌症死亡率以及年龄调整死亡率进行了检查。
在一项横断面研究中，我们对2013年至2021年在巴博勒市登记的所有血液系统肿瘤死亡病例进行了分析。为了估算人口数量，使用了最新的人口普查数据。每种血液系统恶性肿瘤的死亡率和趋势以粗死亡率（CMR）和年龄标准化死亡率（ASMR）报告。
总共有357例死亡（占所有癌症相关死亡的10.8%）归因于血液系统肿瘤，平均年龄为61.9±19.3岁。血液系统肿瘤的粗死亡率和年龄调整死亡率分别从2013年的每10万人3.1例和2.7例增加到2021年的每10万人8.1例和6.9例。血液系统癌症的死亡率趋势在两个性别中均随年龄每十年增加（<0.001）。此外，在检查每种血液系统肿瘤的趋势时，除霍奇金淋巴瘤观察到的一致趋势（=0.247）外，非霍奇金淋巴瘤（=0.033）、多发性骨髓瘤（=0.002）和白血病（<0.001）等肿瘤有显著增加。
巴博勒市血液系统恶性肿瘤的趋势在所有年龄组和两个性别中都在增加。本研究强调需要有效的预防和治疗策略，包括改善癌症护理的可及性、加强对血液系统恶性肿瘤家庭的监测以及减少可改变的风险因素。此外，有必要进行进一步研究以制定针对性的干预措施。
