Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA.
Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia; School of Women's and Children's Health, UNSW Medicine, UNSW Sydney, Kensington, NSW, Australia.
Lancet. 2022 Apr 16;399(10334):1561-1572. doi: 10.1016/S0140-6736(22)00460-3.
Worldwide advances in treatment and supportive care for children and adolescents with cancer have resulted in a increasing population of survivors growing into adulthood. Yet, this population is at very high risk of late occurring health problems, including significant morbidity and early mortality. Unique barriers to high-quality care for this group include knowledge gaps among both providers and survivors as well as fragmented health-care delivery during the transition from paediatric to adult care settings. Survivors of childhood and adolescent cancer are at risk for a range of late-occuring side-effects from treatment, including cardiac, endocrine, pulmonary, fertility, renal, psychological, cognitive, and socio-developmental impairments. Care coordination and transition to adult care are substantial challenges, but can be empowering for survivors and improve outcomes, and could be facilitated by clear, effective communication and support for self-management. Resources for adult clinical care teams and primary care providers include late-effects surveillance guidelines and web-based support services.
全球范围内,儿童和青少年癌症的治疗和支持性护理取得了进展,这导致越来越多的幸存者成长为成年人。然而,这群人患后期健康问题的风险非常高,包括严重的发病率和早期死亡率。为这群人提供高质量护理的独特障碍包括提供者和幸存者之间的知识差距,以及从儿科到成人护理环境过渡期间分散的医疗保健服务。儿童期和青少年期癌症幸存者面临一系列治疗后迟发性副作用的风险,包括心脏、内分泌、肺部、生育能力、肾脏、心理、认知和社会发展障碍。护理协调和向成人护理的过渡是巨大的挑战,但对幸存者来说是赋权的,可以改善结果,并可以通过清晰有效的沟通和自我管理支持来促进。成人临床护理团队和初级保健提供者的资源包括晚期效应监测指南和基于网络的支持服务。