伊朗东南部早产儿视网膜病变的发病率及危险因素：一项回顾性队列研究
Incidence and Risk Factors of Retinopathy of Prematurity in Southeastern Iran: A Retrospective Cohort Study.
作者信息
Maleki Alireza, Sargazi Meisam, Yousefian Ali, Sarhadi Saeedeh, Mollaei Maryam, Mohammadi Seyed Omid
机构信息
Alzahra Eye Hospital Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Department of Ophthalmology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
出版信息
Arch Iran Med. 2024 Dec 1;27(12):660-666. doi: 10.34172/aim.31070.
BACKGROUND
Retinopathy of prematurity (ROP) is a significant cause of preventable premature infant vision loss. Many studies have reported different risk factors depending on the region. In this study, we evaluated the incidence of ROP and associated risk factors in a referral eye hospital in southeastern Iran.
METHODS
This was a retrospective cohort study of preterm infants with birth weight (BW)≤2000 g or gestational age (GA)≤34 weeks and infants with GA between 34-37 weeks or GA<37 weeks and BW>2000 g referred by their pediatricians to our center from March 2022 until March 2023.
RESULTS
Totally, 920 infants met the inclusion criteria for the study. The incidence of ROP and ROP requiring treatment was 20.2% and 3.58% respectively. Results of logistic regression analysis showed higher GA and BW as protective factors against ROP occurrence. History of blood transfusion and phototherapy increased ROP development.
CONCLUSION
Lower GA, lower BW, history of blood transfusion, and phototherapy were associated with ROP development. Phototherapy decreased the need for treatment among ROP patients.
背景
早产儿视网膜病变（ROP）是可预防的早产儿视力丧失的重要原因。许多研究报告了不同地区的不同风险因素。在本研究中，我们评估了伊朗东南部一家转诊眼科医院中ROP的发病率及相关风险因素。
方法
这是一项回顾性队列研究，研究对象为2022年3月至2023年3月期间由儿科医生转诊至我们中心的出生体重（BW）≤2000g或胎龄（GA）≤34周的早产儿，以及GA在34 - 37周之间或GA<37周且BW>2000g的婴儿。
结果
共有920名婴儿符合该研究的纳入标准。ROP的发病率及需要治疗的ROP发病率分别为20.2%和3.58%。逻辑回归分析结果显示，较高的GA和BW是预防ROP发生的保护因素。输血史和光疗会增加ROP的发生。
结论
较低的GA、较低的BW、输血史和光疗与ROP的发生有关。光疗减少了ROP患者的治疗需求。
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