Mathieu Laurent, Ghabi Ammar, Druel Thibault, Gayito Adagba René Ayaovi, Grosset Antoine, Durand Marjorie, Collombet Jean-Marc, Andro Christophe
Department of Orthopedic, Trauma and Reconstructive Surgery, Percy Military Hospital, 101 avenue Henri Barbusse, Clamart, 92140, France.
Department of Hand and Upper Extremity Surgery, Edouard Herriot Hospital, 5 place d'Arsonval, Lyon, 69003, France.
Eur J Trauma Emerg Surg. 2025 Feb 1;51(1):90. doi: 10.1007/s00068-024-02722-5.
The management of extensive bone defects presents a significant challenge for military orthopedic surgeons, especially in the context of a high intensity conflict or when patients are fully treated in the field. The objective was to evaluate the induced membrane technique (IMT) including a multiperforated non-vascularized fibular graft (NVFG) for the reconstruction of massive bone defects performed in both the ideal conditions of military trauma centers and the austere environment of forward surgical units.
A retrospective case study was conducted on patients who underwent the above procedure in various care settings between January 2019 and June 2023. Outcomes measured included the achievement of bone union, time to bone union, and the healing index (time to bone healing/length of reconstructed bone). Functional assessment was based on the Quick-DASH score and the lower extremity functional scale (LEFS).
Nine patients with a mean age of 37 years were included: five were managed in a role 4 medical treatment facility (MTF) and four in a role 2 MTF. Five patients had an infected bone defect before IMT application. After debridement, the mean bone defect length was 14 cm, and the mean bone defect volume was 190 cm. The mean interval between stages was 15 weeks. The mean follow-up was 20 months. Bone union was achieved in 8/9 cases with a mean time of 8.1 months and a mean healing index of 0.58 month/cm. Only the patient with persistent humeral nonunion had a poor DASH-score. The mean LEFS was 68%.
In this small cohort, IMT including a multiperforated NVFG enabled successful reconstruction of massive bone defects in the femur, tibia, and humerus, even in the austere environment of forward surgical units, provided that prior infection control had been achieved.
大面积骨缺损的处理对军队骨科医生而言是一项重大挑战,尤其是在高强度冲突情况下,或者患者在战地接受全程治疗时。目的是评估诱导膜技术(IMT),包括带多个穿孔的非血管化腓骨移植(NVFG),用于在军队创伤中心的理想条件以及前沿外科单位的艰苦环境下进行的大块骨缺损重建。
对2019年1月至2023年6月期间在不同医疗环境下接受上述手术的患者进行回顾性病例研究。测量的结果包括骨愈合的实现情况、骨愈合时间以及愈合指数(骨愈合时间/重建骨长度)。功能评估基于快速残疾评定量表(Quick-DASH)评分和下肢功能量表(LEFS)。
纳入9例平均年龄为37岁的患者:5例在4级医疗救治机构(MTF)接受治疗,4例在2级MTF接受治疗。5例患者在应用IMT前存在感染性骨缺损。清创后,平均骨缺损长度为14厘米,平均骨缺损体积为190立方厘米。各阶段之间的平均间隔为15周。平均随访时间为20个月。9例中有8例实现了骨愈合,平均时间为8.1个月,平均愈合指数为0.58个月/厘米。只有肱骨持续不愈合的患者DASH评分较差。平均LEFS为68%。
在这个小队列中,包括带多个穿孔的NVFG的IMT能够成功重建股骨、胫骨和肱骨的大块骨缺损,即使是在前沿外科单位的艰苦环境下,前提是已实现先前的感染控制。