意外发现的黑色染色淋巴结：一例报告。
Unexpected black-stained lymph nodes: A case report.
作者信息
Chen Hao, Huang Yibo, Wang Feng, Tao Liang, Wang Meng
机构信息
Division of Gastric Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Division of Gastric Surgery, Department of General Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing 210008, China.
出版信息
Int J Surg Case Rep. 2025 Feb;127:110930. doi: 10.1016/j.ijscr.2025.110930. Epub 2025 Jan 23.
BACKGROUND AND IMPORTANCE
Currently, radical gastrectomy for gastric cancer is usually combined with lymph node tracing technology to ensure the complete removal of metastatic lymph nodes. Our case demonstrates that bismuth compounds may be useful as lymph node tracers in radical gastrectomy.
CASE PRESENTATION
A 37-year-old man who was confirmed the diagnosis of gastric cancer was found to have black-stained lymph nodes during the surgical resection. The patient's medication history, pathological analysis and Inductively coupled plasma mass spectrometry (ICP-MS) confirmed the presence of dark particle deposited in the black-stained lymph nodes and the black particles were likely some form of bismuth compound.
CLINICAL DISCUSSION
At present, lymph node tracers used in clinical practice have certain unavoidable limitations. It is necessary to discover new lymph node tracers.
CONCLUSION
our case highlights a new potential avenue for the development of lymph node tracers in radical gastrectomy. However, it is essential to remain vigilant regarding the possible adverse consequences of overdose in clinical practice.
背景与重要性
目前，胃癌根治性胃切除术通常结合淋巴结示踪技术，以确保彻底清除转移性淋巴结。我们的病例表明，铋化合物可能可用作根治性胃切除术中的淋巴结示踪剂。
病例介绍
一名确诊为胃癌的37岁男性在手术切除过程中发现淋巴结被染黑。患者的用药史、病理分析和电感耦合等离子体质谱法（ICP-MS）证实，黑色染色淋巴结中存在深色颗粒沉积物，且黑色颗粒可能是某种形式的铋化合物。
临床讨论
目前，临床实践中使用的淋巴结示踪剂存在一定不可避免的局限性。有必要发现新的淋巴结示踪剂。
结论
我们的病例突出了根治性胃切除术中淋巴结示踪剂开发的一条新的潜在途径。然而，在临床实践中，必须对过量使用可能产生的不良后果保持警惕。
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