Lv Liangliang, Li Chang, Wei Wenjing, Sun Shuyi, Ren Xiaoxuan, Pan Xiaodong, Li Gongping
School of Nuclear Science and Technology, Lanzhou University, Lanzhou, China.
Key Laboratory of Special Functional Materials and Structural Design, Ministry of Education, Lanzhou University, Lanzhou, China.
Med Phys. 2025 Apr;52(4):2089-2105. doi: 10.1002/mp.17636. Epub 2025 Feb 2.
Sparse-view CT shortens scan time and reduces radiation dose but results in severe streak artifacts due to insufficient sampling data. Deep learning methods can now suppress these artifacts and improve image quality in sparse-view CT reconstruction.
The quality of sparse-view CT reconstructed images can still be improved. Additionally, the interpretability of deep learning-based optimization methods for these reconstruction images is lacking, and the role of different network layers in artifact removal requires further study. Moreover, the optimization capability of these methods for reconstruction images from various sparse views needs enhancement. This study aims to improve the network's optimization ability for sparse-view reconstructed images, enhance interpretability, and boost generalization by establishing multiple network structures and datasets.
In this paper, we developed a sparse-view CT reconstruction images improvement network (SRII-Net) based on U-Net. We added a copy pathway in the network and designed a residual image output block to boost the network's performance. Multiple networks with different connectivity structures were established using SRII-Net to analyze the contribution of each layer to artifact removal, improving the network's interpretability. Additionally, we created multiple datasets with reconstructed images of various sampling views to train and test the proposed network, investigating how these datasets from different sampling views affect the network's generalization ability.
The results show that the proposed method outperforms current networks, with significant improvements in metrics like PSNR and SSIM. Image optimization time is at the millisecond level. By comparing the performance of different network structures, we've identified the impact of various hierarchical structures. The image detail information learned by shallow layers and the high-level abstract feature information learned by deep layers play a crucial role in optimizing sparse-view CT reconstruction images. Training the network with multiple mixed datasets revealed that, under a certain amount of data, selecting the appropriate categories of sampling views and their corresponding samples can effectively enhance the network's optimization ability for reconstructing images with different sampling views.
The network in this paper effectively suppresses artifacts in reconstructed images with different sparse views, improving generalization. We have also created diverse network structures and datasets to deepen the understanding of artifact removal in deep learning networks, offering insights for noise reduction and image enhancement in other imaging methods.
稀疏视图CT缩短了扫描时间并降低了辐射剂量,但由于采样数据不足会导致严重的条纹伪影。深度学习方法现在可以抑制这些伪影并提高稀疏视图CT重建中的图像质量。
稀疏视图CT重建图像的质量仍有提升空间。此外,基于深度学习的这些重建图像优化方法缺乏可解释性,不同网络层在去除伪影中的作用需要进一步研究。而且,这些方法对来自各种稀疏视图的重建图像的优化能力有待增强。本研究旨在通过建立多种网络结构和数据集,提高网络对稀疏视图重建图像的优化能力,增强可解释性,并提升泛化能力。
在本文中,我们基于U-Net开发了一种稀疏视图CT重建图像改进网络(SRII-Net)。我们在网络中添加了一个复制路径,并设计了一个残差图像输出块来提升网络性能。使用SRII-Net建立了具有不同连接结构的多个网络,以分析各层对去除伪影的贡献,提高网络的可解释性。此外,我们创建了多个包含各种采样视图重建图像的数据集来训练和测试所提出的网络,研究这些来自不同采样视图的数据集如何影响网络的泛化能力。
结果表明,所提出的方法优于当前网络,在PSNR和SSIM等指标上有显著提升。图像优化时间处于毫秒级。通过比较不同网络结构的性能,我们确定了各种层次结构的影响。浅层学习到的图像细节信息和深层学习到的高级抽象特征信息在优化稀疏视图CT重建图像中起着关键作用。用多个混合数据集训练网络表明,在一定量的数据下,选择合适的采样视图类别及其相应样本可以有效增强网络对不同采样视图重建图像的优化能力。
本文中的网络有效地抑制了不同稀疏视图重建图像中的伪影,提高了泛化能力。我们还创建了多样的网络结构和数据集,以加深对深度学习网络中去除伪影的理解,为其他成像方法中的降噪和图像增强提供了见解。