Lu Xunlai, Liu Shengfu, Ma Luyao, Zhu Junwei, Cao Wei
Department of Cardiovascular Surgery, Northeast Yunnan Central Hospital, Zhaotong, China.
Cancer Rep (Hoboken). 2025 Feb;8(2):e70104. doi: 10.1002/cnr2.70104.
Synovial sarcoma, a highly aggressive soft tissue sarcoma, is mostly seen among young people and tends to occur in the extremities. It most commonly metastasizes to the lungs, and symptoms such as chest tightness, shortness of breath, and coughing are common after metastasis. However, multiple spontaneous pneumothorax is relatively rare. This article aims to further enhance the understanding of synovial sarcoma by introducing a case of pulmonary metastasis after surgery for synovial sarcoma originating from the sole of the foot and reviewing relevant literature.
The Cardiothoracic Surgery Department of the Northeast Yunnan Central Hospital Region admitted a 40-year-old male patient. He had previously undergone surgery for synovial sarcoma on the left foot dorsum. Seven years after the surgery, the patient experienced two spontaneous pneumothorax events. A chest CT scan revealed solid nodules in the upper lobe of the left lung. Our department performed surgical removal, and pathology confirmed metastatic pulmonary synovial sarcoma. After the surgery, the patient's symptoms improved significantly, and there were no further pneumothorax attacks. The patient was then transferred to the oncology department for further treatment to improve prognosis.
Pulmonary metastasis of synovial sarcoma is not uncommon, and a considerable number of patients are found to have no surgical opportunity when diagnosed. In this case, the patient presented with a single solid nodule, and we adopted surgery as the first-line treatment, combined with a comprehensive treatment plan of postoperative chemotherapy to further improve the patient's prognosis.
滑膜肉瘤是一种侵袭性很强的软组织肉瘤，多见于年轻人，好发于四肢。它最常转移至肺部，转移后常见胸闷、气短、咳嗽等症状。然而，多发性自发性气胸相对少见。本文旨在通过介绍1例足底起源的滑膜肉瘤术后肺转移病例并复习相关文献，进一步提高对滑膜肉瘤的认识。
滇东北区域中心医院心胸外科收治了1例40岁男性患者。他曾因左足背滑膜肉瘤接受手术治疗。术后7年，患者发生了2次自发性气胸事件。胸部CT扫描显示左肺上叶有实性结节。我科进行了手术切除，病理证实为肺转移性滑膜肉瘤。术后患者症状明显改善，未再发生气胸发作。随后患者被转至肿瘤科进行进一步治疗以改善预后。
滑膜肉瘤肺转移并不少见，相当一部分患者确诊时已无手术机会。本病例中，患者表现为单个实性结节，我们采用手术作为一线治疗，并结合术后化疗的综合治疗方案，进一步改善了患者的预后。
