Wang Heyong, Wang Jun, Chen Yang, Yang Dianxing, Xiong Lanyue
School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Department of Nephrology, Sichuan Integrative Medicine Hospital, Chengdu, China.
Front Med (Lausanne). 2025 Jan 17;11:1480832. doi: 10.3389/fmed.2024.1480832. eCollection 2024.
This study analyzed literature on traditional Chinese medicine (TCM) in treating chronic kidney disease (CKD) to identify research trends and provide guidance for future studies and clinical practice.
The study used data from Web of Science from 2000 to 2024 to analyze English-language literature on CKD and TCM. Bibliometric analysis was done using R software and the bibliometric package, with scientific mapping and visualization analysis conducted using tools like Citespace, VOSviewer, and ScimagoGraphica to explore research trends and connections.
This study revealed that a total of 1,153 relevant documents were retrieved, and the number of published articles showed an increasing trend, reaching a peak in 2022. In terms of article publication, China ranked first with 760 articles, closely followed by the United States with 132 articles. Guangzhou University of Traditional Chinese Medicine published 60 papers, the most among academic institutions, followed by Shanghai University of Traditional Chinese Medicine with 54 papers. In terms of individual authors, Liu Xinhui holds the record for the highest number of published articles, totaling 17, followed by Li Ping and Li Shunmin. The prevalent keywords include "chronic kidney disease," "TCM," and "oxidative stress." Currently, the prominent areas of research interest include network pharmacology, gut microbiota, oxidative stress, and related topics. The current research trend in this field is towards the adoption of novel methodologies such as network pharmacology and the emphasis on exploring the relationship between gut microbiota and CKD.
Global research on TCM in the treatment of CKD is showing a positive development trend, but further research on safety, efficacy evaluation, and international cooperation is still needed. The development trend is to adopt new scientific research methods and focus on exploring the mechanism of TCM in treating CKD.
本研究分析了中医治疗慢性肾脏病（CKD）的文献，以确定研究趋势，并为未来研究和临床实践提供指导。
本研究使用2000年至2024年Web of Science的数据，分析关于CKD和中医的英文文献。使用R软件和文献计量学软件包进行文献计量分析，使用Citespace、VOSviewer和ScimagoGraphica等工具进行科学绘图和可视化分析，以探索研究趋势和联系。
本研究显示，共检索到1153篇相关文献，发表文章数量呈上升趋势，在2022年达到峰值。在文章发表方面，中国以760篇位居第一，紧随其后的是美国，有132篇。广州中医药大学发表了60篇论文，在学术机构中排名第一，其次是上海中医药大学，有54篇。在个人作者方面，刘新慧发表文章数量最多，共计17篇，其次是李平、李顺民。常见关键词包括“慢性肾脏病”“中医”和“氧化应激”。目前，突出的研究兴趣领域包括网络药理学、肠道微生物群、氧化应激及相关主题。该领域当前的研究趋势是采用网络药理学等新方法，并强调探索肠道微生物群与CKD之间的关系。
全球中医治疗CKD的研究呈积极发展趋势，但在安全性、疗效评估和国际合作方面仍需进一步研究。发展趋势是采用新的科研方法，重点探索中医治疗CKD的机制。
