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帕金森病患者步态物理治疗结合运动想象:一项随机对照GAITimagery试验方案

Gait physiotherapy with motor imagery in people with Parkinson's disease: a protocol for randomized control GAITimagery trial.

作者信息

San Martín Valenzuela Constanza, Ramírez Murcia Esperanza, Aznar-Requena Estela, García Sotolongo Dalia, Rosas-Martín Rebeca, Sánchez-Sánchez M Luz

机构信息

Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Valencia, Spain.

Unit of Personal Autonomy, Dependency and Mental Disorder Assessment, Faculty of Medicine, University of Valencia, INCLIVA Biomedical Research Institute, Valencia, Spain.

出版信息

Front Neurol. 2025 Jan 17;15:1508043. doi: 10.3389/fneur.2024.1508043. eCollection 2024.

Abstract

INTRODUCTION

According to people with Parkinson's disease (PD), gait impairments are the most disabling motor symptoms of PD. Recently, motor imagery (MI) has gained notoriety as a gait training technique due to the flexibility of its use, however, it has not been demonstrated that causes a superior effect when included in physiotherapy. This study aims to determine if gait training combined with MI has a greater effect on the gait of people with PD than just gait training.

METHODS

The GAITimagery is designed as a double-blind, randomized control trial, including a convenience sample in 2 parallel groups (1:1) with two interventions of 2 sessions per week during 6-week and 8-week follow-up. The initial recruitment will be 88 participants with idiopathic PD and unimpaired cognition state, who will be randomly divided into two groups: GAITimagery (GiG) or the active control Gait group (GaG). Both will perform the same gait exercises but only GiG will include MI training. Gait speed is the primary outcome, while Maximum gait speed (m/s) and Gait speed variability are the secondary results. The tertiary outcomes are related to Quality of life, Daily life activities, Freezing of gait, Balance, Mobility, and Gait performance measures to psychometrics and biomechanics instruments. All results will be measured at baseline (t0), post-training (t1), and follow-up assessment (t2) 8 weeks after finished physiotherapy programs.

DISCUSSION

The GAITimagery program standardizes the application of MI exercises related to the improvement of parkinsonian gait at the same time that monitoring the vividness referred by the participants session by session. The effectiveness of this MI-exclusive program includes subjective and objective measurement tools to detect minimal changes after training. This still-to-be-finish study will support the therapeutic decisions on whether or not to allocate session time to imagery exercises depending on the effect size achieved and the comparison with a control gait training.

摘要

引言

据帕金森病(PD)患者称,步态障碍是PD最致残的运动症状。最近,运动想象(MI)作为一种步态训练技术而声名鹊起,因为其使用具有灵活性,然而,尚未证明将其纳入物理治疗时会产生更优效果。本研究旨在确定与单纯的步态训练相比,结合MI的步态训练对PD患者的步态是否有更大影响。

方法

GAITimagery被设计为一项双盲、随机对照试验,包括一个便利样本,分为2个平行组(1:1),在6周和8周的随访期间,每组每周进行2次干预,每次干预2节训练课。最初招募88名特发性PD且认知状态未受损的参与者,他们将被随机分为两组:GAITimagery(GiG)组或主动对照步态组(GaG)。两组都将进行相同的步态练习,但只有GiG组将包括MI训练。步态速度是主要结果,而最大步态速度(米/秒)和步态速度变异性是次要结果。三级结果与生活质量、日常生活活动、步态冻结、平衡、活动能力以及心理测量学和生物力学仪器的步态表现测量有关。所有结果将在基线(t0)、训练后(t1)以及完成物理治疗计划8周后的随访评估(t2)时进行测量。

讨论

GAITimagery计划规范了与改善帕金森步态相关的MI练习的应用,同时逐节监测参与者报告的生动程度。这个仅包含MI的计划的有效性包括主观和客观测量工具,以检测训练后的微小变化。这项尚未完成的研究将根据所取得的效应大小以及与对照步态训练的比较,为是否分配训练时间进行想象练习的治疗决策提供支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/131b/11783183/9e41db09314b/fneur-15-1508043-g001.jpg

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