虚拟现实技术与运动想象联合对帕金森病患者平衡、运动功能及日常生活活动能力的影响：一项随机对照试验。
Combined effects of virtual reality techniques and motor imagery on balance, motor function and activities of daily living in patients with Parkinson's disease: a randomized controlled trial.
机构信息
University Institute of Physical Therapy, Faculty of Allied Health Sciences, University of Lahore, 1 KM Defence Road, Lahore, 4200, Pakistan.
Riphah College of Rehabilitation and Allied Health Sciences, Riphah International University, Faisalabad Campus, Faisalabad, Pakistan.
出版信息
BMC Geriatr. 2022 Apr 30;22(1):381. doi: 10.1186/s12877-022-03035-1.
BACKGROUND
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, impairing balance and motor function. Virtual reality (VR) and motor imagery (MI) are emerging techniques for rehabilitating people with PD. VR and MI combination have not been studied in PD patients. This study was conducted to investigate the combined effects of VR and MI techniques on the balance, motor function, and activities of daily living (ADLs) of patients with PD.
METHODS
This study was a single-centered, two-armed, parallel-designed randomized controlled trial. A total of 44 patients of either gender who had idiopathic PD were randomly allocated into two groups using lottery methods. Both groups received Physical therapy (PT) treatment, while the experimental group (N: 20) received VR and MI in addition to PT. Both groups received assigned treatment for three days a week on alternate days for 12 weeks. The Unified Parkinson's Disease Rating Scale (UPDRS) (parts II and III), Berg Balance Scale (BBS), and Activities-specific Balance Confidence (ABC) Scale were used as outcome measures for motor function, balance, and ADLs. The baseline, 6, and 12 weeks of treatment were assessed, with a 16 week follow-up to measure retention. The data was analysed using SPSS 24.
RESULTS
The experimental group showed significant improvement in motor function than the control group on the UPDRS part III, with 32.45±3.98 vs. 31.86±4.62 before and 15.05±7.16 vs. 25.52±7.36 at 12-weeks, and a p-value < 0.001. At 12 weeks, the experimental group's BBS scores improved from 38.95±3.23 to 51.36±2.83, with p-value < 0.001. At 12 weeks, the experimental group's balance confidence improved considerably, from 59.26±5.87to 81.01±6.14, with a p-value of < 0.001. The experimental group's ADL scores improved as well, going from 22.00±4.64 to 13.07±4.005 after 12 weeks, with a p-value of < 0.001.
CONCLUSION
VR with MI techniques in addition to routine PT significantly improved motor function, balance, and ADLs in PD patients compared to PT alone.
TRIAL REGISTRATION
IRCT20200221046567N1 . Date of registration: 01/04/2020.
背景
帕金森病（PD）是第二大常见的神经退行性疾病，会损害平衡和运动功能。虚拟现实（VR）和运动想象（MI）是用于康复 PD 患者的新兴技术。尚未在 PD 患者中研究 VR 和 MI 的组合。本研究旨在探讨 VR 和 MI 技术联合应用对 PD 患者平衡、运动功能和日常生活活动（ADL）的影响。
方法
这是一项单中心、双臂、平行设计的随机对照试验。采用抽签法将 44 名性别不限的特发性 PD 患者随机分为两组。两组均接受物理治疗（PT）治疗，实验组（N：20）除接受 PT 外，还接受 VR 和 MI。两组均在 12 周内每周 3 天，隔日接受治疗。采用统一帕金森病评定量表（UPDRS）（第 II 部分和第 III 部分）、伯格平衡量表（BBS）和活动特异性平衡信心量表（ABC）作为运动功能、平衡和 ADL 的结局指标。评估治疗前、6 周和 12 周的基线，16 周随访以测量保留率。数据采用 SPSS 24 进行分析。
结果
实验组在 UPDRS 第 III 部分的运动功能方面明显优于对照组，分别为 32.45±3.98 与 31.86±4.62 （治疗前）和 15.05±7.16 与 25.52±7.36 （治疗 12 周后），p 值均<0.001。12 周时，实验组 BBS 评分从 38.95±3.23 提高到 51.36±2.83，p 值<0.001。12 周时，实验组的平衡信心显著提高，从 59.26±5.87 提高到 81.01±6.14，p 值<0.001。实验组的 ADL 评分也有所改善，12 周后从 22.00±4.64 降至 13.07±4.005，p 值<0.001。
结论
与单独进行 PT 相比，VR 联合 MI 技术除常规 PT 外，还能显著改善 PD 患者的运动功能、平衡和 ADL。
试验注册
IRCT20200221046567N1。注册日期：2020 年 4 月 1 日。
Zotero 插件