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1例胰腺和肾脏移植受者剖宫产术中肾移植损伤的病例。

A case of kidney graft injury during cesarean section in a pancreas and kidney transplantation recipient.

作者信息

Aida Noriko, Nishio Eiji, Sekiya Takao, Aida Naohiro, Ito Taihei, Kenmochi Takashi, Nishizawa Haruki

机构信息

Women's Health Clinic Kariyaginza, Kariya, Aichi, Japan.

Department of Obstetrics and Gynecology, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.

出版信息

Fujita Med J. 2025 Feb;11(1):52-53. doi: 10.20407/fmj.2024-008. Epub 2024 Oct 31.

Abstract

Although organ transplantation is becoming general practice, little is known about the safety of delivery. This is the first known case that describes injury to the kidney by the uterine fundal pressure maneuver during cesarean section in a pancreas and kidney transplant recipient. A 40-year-old pregnant woman (gravida 0, para 0) was referred to our clinic. She had undergone living donor kidney transplantation 11 years earlier and brain-dead donor pancreas transplantation 1 year earlier owing to type 1 diabetes. Cesarean section was indicated when the patient's blood pressure was 150/100 mmHg at 37 weeks. We pushed the uterine fundus during delivery of the infant, with our usual caution. Serum creatinine levels were 1.6-2.6 mg/dl postoperatively. As this elevation was considered to be due to kidney graft dysfunction, we performed computed tomography, which revealed a hematoma around the kidney graft. Fifteen days after the cesarean section, surgical removal of the hematoma was performed by the transplant surgery team. Following hematoma removal, the serum creatinine level decreased to <1.4 mg/dl. We present a case of kidney graft injury during cesarean section in a pancreas and kidney transplant recipient.

摘要

尽管器官移植已逐渐成为常规手术,但关于分娩安全性的了解却很少。这是首例已知的关于胰腺和肾脏移植受者剖宫产术中子宫底按压操作导致肾损伤的病例。一名40岁孕妇(孕0产0)转诊至我院。她11年前接受了活体供肾移植,1年前因1型糖尿病接受了脑死亡供体胰腺移植。孕37周时患者血压为150/100 mmHg,遂行剖宫产术。分娩时,我们像往常一样小心地按压子宫底。术后血清肌酐水平为1.6 - 2.6 mg/dl。由于认为这种升高是由于肾移植功能障碍所致,我们进行了计算机断层扫描,结果显示肾移植周围有血肿。剖宫产术后15天,移植手术团队对血肿进行了手术清除。血肿清除后,血清肌酐水平降至<1.4 mg/dl。我们报告了一例胰腺和肾脏移植受者剖宫产术中肾移植损伤的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac72/11782938/20f7b1d54e69/fmj-11-052-g001.jpg

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