van Niekerk Jan A, Kleyenstuber Thomas, Jooma Zainub
Department of Anaesthesiology, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Private Practice, Johannesburg, South Africa.
BJA Open. 2025 Jan 17;13:100373. doi: 10.1016/j.bjao.2024.100373. eCollection 2025 Mar.
Caesarean section is a common surgical procedure, accounting for almost a third of all surgical procedures in low- middle-income countries. Enhanced recovery after Caesarean section (ERAC) programmes are rarely implemented in resource-limited settings. This study evaluated a tailored enhanced recovery programme's impact on quality of recovery after elective Caesarean section in a Johannesburg public hospital.
This was a prospective, observational, before-after cohort study. Fifty-two patients (aged ≥18 yr) undergoing elective Caesarean section were analysed, comprising a pre-ERAC cohort (=25), analysed from 8 to 22 April 2024 and a post-ERAC cohort (=27), analysed from 3 to13 June 2024. The primary outcome was postpartum recovery measured by the Obstetric Quality of Recovery-10 score.
There was a significant improvement in Obstetric Quality of Recovery-10 scores post-ERAC, with a difference in medians of 9 between cohorts (95% confidence interval: 6-14; <0.001). There was also a significant reduction in opioid consumption with a median decrease of 10 mg oral morphine equivalent in the post-ERAC cohort in the first 24 h after operation (95% confidence interval: -26 to 6; <0.001). Time to urinary catheter removal, time to first oral intake, time to first mobilisation, and preoperative fasting for liquids all showed significant improvement in the post-ERAC cohort. There was no difference in length of stay and other secondary outcomes.
This study demonstrates that ERAC implementation in a resource-limited setting is feasible and can enhance maternal recovery after elective Caesarean section. These findings highlight the potential for ERAC programs to significantly improve patient-centred outcomes in low-middle income countries.
剖宫产是一种常见的外科手术,在低收入和中等收入国家,几乎占所有外科手术的三分之一。剖宫产术后加速康复(ERAC)方案在资源有限的环境中很少实施。本研究评估了一项量身定制的加速康复方案对约翰内斯堡一家公立医院择期剖宫产术后恢复质量的影响。
这是一项前瞻性、观察性的前后队列研究。分析了52例(年龄≥18岁)接受择期剖宫产的患者,包括一个ERAC前队列(n = 25),于2024年4月8日至22日进行分析,以及一个ERAC后队列(n = 27),于2024年6月3日至13日进行分析。主要结局是通过产科恢复质量-10评分来衡量的产后恢复情况。
ERAC后产科恢复质量-10评分有显著改善,队列之间的中位数差异为9(95%置信区间:6 - 14;P < 0.001)。术后24小时内,ERAC后队列的阿片类药物消耗量也显著减少,口服吗啡当量中位数减少10毫克(95%置信区间:-26至6;P < 0.001)。ERAC后队列在拔除尿管时间、首次经口进食时间、首次活动时间和术前液体禁食时间方面均有显著改善。住院时间和其他次要结局没有差异。
本研究表明,在资源有限的环境中实施ERAC是可行的,并且可以提高择期剖宫产术后的产妇恢复情况。这些发现凸显了ERAC方案在低收入和中等收入国家显著改善以患者为中心的结局的潜力。