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噬菌体AWGoat的分离与注释

Isolation and Annotation of Phage AWGoat.

作者信息

Bolling Caitlyn, Chervenic Chloe, Drake Kate, Griffin Zoe, Jain Isha, Khabir Hala, Ordon Tyler, Padilla Anthony, Showers Rachel, Vences Jose, Walsh Caelan, Workman Wyatt, Bullock Sharon, Pass Michelle, Bates Tonya, Wisner Ellen

机构信息

Department of Biological Sciences, University of North Carolina at Charlotte.

出版信息

MicroPubl Biol. 2025 Jan 16;2025. doi: 10.17912/micropub.biology.001433. eCollection 2025.

DOI:10.17912/micropub.biology.001433
PMID:39897170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11783173/
Abstract

AWGoat, a lytic bacteriophage that infects was isolated from a goat pen in Charlotte, NC. Its genome is 65,496 bp long, with a GC content of 67.1%. Based on gene content similarity, AWGoat is assigned to actinobacteriophage cluster AP. It encodes a putative toxin from a broadly distributed toxin/antitoxin pair and an unusually large minor tail protein.

摘要

AWGoat是一种感染[具体细菌未提及]的裂解性噬菌体,从北卡罗来纳州夏洛特市的一个山羊圈中分离得到。其基因组长度为65,496碱基对,GC含量为67.1%。根据基因含量相似性,AWGoat被归入放线菌噬菌体簇AP。它编码一种来自广泛分布的毒素/抗毒素对的推定毒素和一种异常大的次要尾蛋白。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d02/11783173/c5775f7bafb2/25789430-2025-micropub.biology.001433.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d02/11783173/c5775f7bafb2/25789430-2025-micropub.biology.001433.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d02/11783173/c5775f7bafb2/25789430-2025-micropub.biology.001433.jpg

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Developing Phage Therapy That Overcomes the Evolution of Bacterial Resistance.开发克服细菌耐药性进化的噬菌体疗法。
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