Pastakia Sonak D, Schutz Heidi, Tiruneh Tena, Vivero Ariana Gordillo De, Dodds Lindsey
Purdue University College of Pharmacy, Center for Health Equity and Innovation, Fifth Third Bank Building, 640 Eskenazi Ave, Indianapolis, IN 46202, USA.
Heart to Heart International, 11550 Renner Blvd, Lenexa, KS 66219, USA.
Pract Lab Med. 2025 Jan 10;44:e00450. doi: 10.1016/j.plabm.2025.e00450. eCollection 2025 Apr.
Populations experiencing poverty often lack access to convenient lab tests. This analysis assesses trends observed from a national point of care (POC) lab donation program for free and charitable clinics across the United States.
A total of 16 clinics were selected to receive a comprehensive package of POC lab tests. De-identified data on POC test utilization and results were assessed to descriptively identify trends in utilization (primary objective) and glycemic control (secondary objective). A paired -test was utilized to identify statistically significant changes in HbA1c from baseline to predefined 90-day time intervals for all people living with diabetes (PLWD) and those with a baseline HbA1c ≥ 9.0 % (75 mmol/mol). The main comparison of interest was the change in HbA1c from baseline to 90-179 days.
A total of 17,563 POC tests were completed for 9658 patients with 3223 tests being HbA1c's. In the secondary analysis of PLWD with a baseline HbA1c ≥ 9.0 % (75 mmol/mol), patients who completed an HbA1c between 90 and 179 days (n = 188) demonstrated a statistically significant mean reduction from baseline of -1.2 % (95 % CI, -1.6 % to -0.9 %, < 0.01, -10 mmol/mol [95 % CI, -6 mmol/mol - -14 mmol/mol]).
The provision of POC labs helped support the care populations experiencing poverty received at free and charitable clinics, especially for chronic diseases like diabetes.
贫困人口往往难以获得便捷的实验室检测服务。本分析评估了美国一项针对免费和慈善诊所的全国即时检验（POC）实验室捐赠项目所观察到的趋势。
共挑选了16家诊所，为其提供一整套POC实验室检测。对去识别化的POC检测使用情况和结果数据进行评估，以描述性地确定使用情况（主要目标）和血糖控制情况（次要目标）的趋势。采用配对t检验，确定所有糖尿病患者（PLWD）以及基线糖化血红蛋白（HbA1c）≥9.0%（75 mmol/mol）的患者从基线到预定义的90天时间间隔内HbA1c的统计学显著变化。主要关注的比较是从基线到90 - 179天HbA1c的变化。
共为9658名患者完成了17563次POC检测，其中3223次为HbA1c检测。在对基线HbA1c≥9.0%（75 mmol/mol）的PLWD进行的次要分析中，在90至179天内完成HbA1c检测的患者（n = 188）显示，与基线相比，平均降低了1.2%，具有统计学显著性（95%置信区间，-1.6%至-0.9%，P < 0.01，-10 mmol/mol [95%置信区间，-6 mmol/mol - -14 mmol/mol]）。
即时检验实验室的提供有助于支持免费和慈善诊所为贫困人口提供的医疗服务，特别是对于糖尿病等慢性病。
