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重度大疱性肺气肿:探索危险因素及放射成像的重要性

Severe bullous emphysema: exploring risk factors and the importance of radiography.

作者信息

Colantonio Mark A, Wiley Joshua

机构信息

Department of Medicine, West Virginia University, 1 Medical Center Drive, Morgantown, WV 26506, USA.

出版信息

Radiol Case Rep. 2025 Jan 16;20(4):1863-1866. doi: 10.1016/j.radcr.2025.01.009. eCollection 2025 Apr.

DOI:10.1016/j.radcr.2025.01.009
PMID:39897754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11786998/
Abstract

Bullous emphysema, a subtype of emphysema, is characterized by the irreversible enlargement of air-filled airways greater than 1cm in size. Often time, practitioners focus on smoking duration in pack years, and smoking frequency, rather than smoking onset, when assessing risk for development of bullous emphysema. Distinct radiographic findings on CT imaging can differentiate bullae from other lung pathologies, including lung cysts. Here, we present a young female with diffuse, bullous emphysema without an extensive smoking history. We aim to highlight the importance of smoking onset when determining risk for development bullous emphysema, as well as the role of CT imaging in the diagnosis of lung pathologies.

摘要

大疱性肺气肿是肺气肿的一种亚型,其特征是直径大于1厘米的含气气道不可逆扩大。通常,医生在评估大疱性肺气肿的发病风险时,关注的是吸烟包年数和吸烟频率,而非吸烟起始时间。CT成像上独特的影像学表现可将肺大疱与其他肺部病变(包括肺囊肿)区分开来。在此,我们报告一名年轻女性,患有弥漫性大疱性肺气肿,但无广泛吸烟史。我们旨在强调吸烟起始时间在确定大疱性肺气肿发病风险中的重要性,以及CT成像在肺部病变诊断中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665a/11786998/94c7392e62bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665a/11786998/94c7392e62bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/665a/11786998/94c7392e62bb/gr1.jpg

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本文引用的文献

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Unusual case of bullous emphysema with superimposed pneumonia.合并肺炎的大疱性肺气肿罕见病例。
Radiol Case Rep. 2023 Dec 15;19(3):844-849. doi: 10.1016/j.radcr.2023.10.070. eCollection 2024 Mar.
2
Bilateral giant emphysematous bullae complicate severe bronchial asthma in a young patient: case report.双侧巨大气肿性肺大疱使一名年轻患者的重度支气管哮喘病情复杂化:病例报告。
J Surg Case Rep. 2023 Aug 14;2023(8):rjad470. doi: 10.1093/jscr/rjad470. eCollection 2023 Aug.
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Tobacco Patterns and Risk of Chronic Obstructive Pulmonary Disease: Results From a Cross-Sectional Study.
烟草模式与慢性阻塞性肺疾病风险:一项横断面研究的结果。
Arch Bronconeumol. 2023 Nov;59(11):717-724. doi: 10.1016/j.arbres.2023.07.009. Epub 2023 Jul 14.
4
Both Duration and Pack-Years of Tobacco Smoking Should Be Used for Clinical Practice and Research.吸烟的持续时间和吸烟包年数均应用于临床实践和研究。
Ann Am Thorac Soc. 2020 Jul;17(7):804-806. doi: 10.1513/AnnalsATS.202002-133VP.
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A Stepwise Diagnostic Approach to Cystic Lung Diseases for Radiologists.放射科医师囊性肺病的分步诊断方法。
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A review of α1-antitrypsin deficiency.α1-抗胰蛋白酶缺乏症的综述。
Am J Respir Crit Care Med. 2012 Feb 1;185(3):246-59. doi: 10.1164/rccm.201108-1428CI. Epub 2011 Sep 29.
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