Pompeu Bernardo Fontel, Guedes Lucas Soares de Souza Pinto, Bossi Bruna Maffei, Delgado Lucas Monteiro, Frizzo Camila Sigaud, Gauch Isabelle Rocha, Formiga Fernanda Bellotti, Figueiredo Sergio Mazzola Poli de
Department of Colorectal Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.
USCS - University of São Caetano do Sul, Adress Rua Santo Antônio, 50 - Centro, São Caetano do Sul, São Paulo, SP, 09521-160, Brazil.
Hernia. 2025 Feb 4;29(1):84. doi: 10.1007/s10029-025-03262-6.
The high incidence of parastomal hernia (PSH) has led surgeons to study strategies to minimize PSH, including prophylactic mesh placement during permanent stoma creation. There are several studies on prophylactic mesh for preventing PSH with conflicting results and there is limited information on using 3D funnel meshes and their effectiveness in preventing PSH.
A search was performed on PubMed, Scopus, Cochrane Central Register of Clinical Trials, and Web of Science for studies published up to September 2024. Odds ratios (ORs) and mean differences (MD) with 95% confidence intervals (CIs) were pooled using a random-effects model. Heterogeneity was assessed with I² statistics. Statistical analysis was performed using R Software version 4.4.1 (R Foundation for Statistical Computing).
One randomized controlled trial and six observational studies were included, totaling 585 patients who underwent colorectal surgeries requiring a permanent stoma. Of these, 278 patients (47.5%) received prophylactic funnel meshes, and 307 (52.5%) underwent conventional stoma procedures. Compared to conventional procedures without mesh, the funnel mesh group showed significantly lower rates of PSH (9% vs. 54%; OR 0.07, 95% CI 0.03-0.17, p < 0.001). However, no significant differences were observed in time to PSH development, stoma prolapse, Clavien-Dindo grade 3b complications, stricture, ileus, leak, wound infection, small bowel obstruction, 30-day mortality, operative time, or hospital stay.
In patients undergoing colorectal surgery with a permanent end stoma, prophylactic funnel mesh was associated with lower rates of PSH, but findings remain exploratory and limited by current evidence.
造口旁疝(PSH)的高发病率促使外科医生研究将PSH降至最低的策略,包括在永久性造口创建过程中预防性放置补片。关于预防性补片预防PSH的研究有多项,但结果相互矛盾,且关于使用三维漏斗形补片及其预防PSH有效性的信息有限。
在PubMed、Scopus、Cochrane临床试验中心注册库和Web of Science上检索截至2024年9月发表的研究。使用随机效应模型汇总比值比(OR)和95%置信区间(CI)的平均差(MD)。用I²统计量评估异质性。使用R软件4.4.1版(R统计计算基金会)进行统计分析。
纳入一项随机对照试验和六项观察性研究,共585例接受需要永久性造口的结直肠手术的患者。其中,278例患者(47.5%)接受了预防性漏斗形补片,307例(52.5%)接受了传统造口手术。与未使用补片的传统手术相比,漏斗形补片组的PSH发生率显著更低(9%对54%;OR 0.07,95%CI 0.03 - 0.17,p < 0.001)。然而,在PSH发生时间、造口脱垂、Clavien - Dindo 3b级并发症、狭窄、肠梗阻、渗漏、伤口感染、小肠梗阻、30天死亡率、手术时间或住院时间方面未观察到显著差异。
在接受永久性末端造口的结直肠手术患者中,预防性漏斗形补片与较低的PSH发生率相关,但研究结果仍为探索性,且受当前证据限制。