Nguyen Phung Nguyen The, Heininger Ulrich, Muloiwa Rudzani, von König Carl Heinz Wirsing, Hozbor Daniela, Ong-Lim Anna, Tan Tina Q, Forsyth Kevin
University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
University Children's Hospital Basel, Basel, Switzerland.
IJID Reg. 2024 Dec 27;14:100559. doi: 10.1016/j.ijregi.2024.100559. eCollection 2025 Mar.
The Global Pertussis Initiative met in March 2024 to discuss the burden of pertussis and prevention efforts in six Southeast Asian countries: Cambodia, Indonesia, Malaysia, Singapore, Thailand, and Vietnam. Except for Cambodia, pertussis is a notifiable disease; data accuracy varies within and between countries. Most cases in the region are diagnosed based on clinical suspicion. Whole-cell and acellular pertussis combination vaccines are available, but the composition differs between countries. Immunization against pertussis is well-established, but policies regarding boosting vary. Vaccination in pregnancy represents a still-neglected opportunity to protect infants. The Global Pertussis Initiative recommends enacting vaccination in pregnancy in countries without and increasing coverage in countries with policies already in place. There is a need to correct the misperception that pertussis affects children exclusively and that childhood vaccines provide lifelong protection. Education is key to widespread understanding of the threat of pertussis and removing barriers to vaccination in Southeast Asia.
全球百日咳倡议组织于2024年3月召开会议，讨论柬埔寨、印度尼西亚、马来西亚、新加坡、泰国和越南这六个东南亚国家的百日咳负担及预防措施。除柬埔寨外，百日咳属于法定报告疾病；各国国内及国与国之间的数据准确性存在差异。该地区的大多数病例是基于临床怀疑进行诊断的。全细胞和无细胞百日咳联合疫苗均有供应，但各国的疫苗成分有所不同。百日咳免疫接种已深入人心，但加强免疫的政策各不相同。孕期接种疫苗是保护婴儿的一个仍被忽视的机会。全球百日咳倡议组织建议在尚未实施孕期接种疫苗的国家推行此项措施，并在已有相关政策的国家提高覆盖率。有必要纠正那种认为百日咳只影响儿童且儿童疫苗能提供终身保护的错误观念。开展教育对于在东南亚广泛认识百日咳威胁并消除疫苗接种障碍至关重要。
