Skurok Philip, Johnston Brian W, Brown Emma, Timothy Caroline, Morse Christopher, Turton Peter
Intensive Care Unit Warrington and Halton Hospitals NHS Trust Warrington UK.
Liverpool Centre for Cardiovascular Sciences University of Liverpool Liverpool UK.
Health Sci Rep. 2025 Feb 3;8(2):e70337. doi: 10.1002/hsr2.70337. eCollection 2025 Feb.
Post Extubation Dysphagia (PED) is a common consequence of mechanical ventilation. Muscular weakness and atrophy are potential causes. Expiratory Muscle Strength Training (EMST) is a technique whereby a subject exhales against a resistance, strengthening the muscles of expiration. There is evidence that EMST causes activation and hypertrophy of the muscles of swallowing, with clinical evidence that it improves swallowing in certain populations. The aim of this systematic review is to collate the existing literature concerning evaluation of swallowing after extubation, and whether EMST positively affects these measures.
We will perform a systematic review of the literature by searching electronic databases (Pubmed, Medline, EMBASE, and the Cochrane Library), for articles where EMST has been performed (alone or in conjunction with inspiratory muscle training), in patients who have been liberated from a period of mechanical ventilation. We will identify studies that evaluate swallowing after extubation, listing the methods used to evaluate swallowing and data will be extracted from studies evaluating the impact EMST has on these measures.
We will undertake meta-analysis if data permits. Risk of bias will be assessed using the Risk of Bias 2 tool or the Newcastle Ottawa Score for randomized and non-randomized trials. We will use The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess the quality of evidence.
The results of this systematic review will enable us to assess the current literature on the use of EMST in critical care, and whether the intervention improves swallowing and respiratory outcomes. : 42023444479.
拔管后吞咽困难(PED)是机械通气的常见后果。肌肉无力和萎缩是潜在原因。呼气肌力量训练(EMST)是一种让受试者对抗阻力呼气以增强呼气肌的技术。有证据表明,EMST可引起吞咽肌的激活和肥大,并有临床证据显示其能改善特定人群的吞咽功能。本系统评价的目的是整理现有关于拔管后吞咽功能评估的文献,以及EMST是否对这些指标有积极影响。
我们将通过检索电子数据库(PubMed、Medline、EMBASE和Cochrane图书馆)对文献进行系统评价,查找在脱离机械通气一段时间的患者中进行EMST(单独或与吸气肌训练联合)的文章。我们将识别评估拔管后吞咽功能的研究,列出用于评估吞咽功能的方法,并从评估EMST对这些指标影响的研究中提取数据。
如果数据允许,我们将进行荟萃分析。使用偏倚风险2工具或纽卡斯尔渥太华量表对随机和非随机试验的偏倚风险进行评估。我们将采用推荐分级评估、制定与评价(GRADE)方法评估证据质量。
本系统评价的结果将使我们能够评估目前关于在重症监护中使用EMST的文献,以及该干预措施是否能改善吞咽和呼吸结局。 :42023444479。