Metaferia Yeshi, Seid Abdurahaman, Fenta Genet Molla, Weldehanna Daniel Gebretsadik, Adamu Aderaw, Gedefie Alemu
Department of Medical Laboratory Sciences, College of Medicine and Health Sciences Wollo University Dessie Ethiopia.
Health Sci Rep. 2025 Feb 3;8(2):e70410. doi: 10.1002/hsr2.70410. eCollection 2025 Feb.
and malaria share a similar epidemiological distribution or co-endemicity. Co-infection are a global public health burden where epidemiological evidence is crucial to taking evidence-based intervention. Thus, the aim of this study was to assess the prevalence and associated factors of and other intestinal Helminthes co-infection among malaria positive patients in malaria endemic areas of Northeast Ethiopia.
A cross-sectional study was conducted from September 2018 to June 2019 among randomly recruited 145 microscopically confirmed malaria patients in Kemisse and Chefa Robit, Northeast Ethiopia. A pre-tested semi-structured questionnaire was used for sociodemographic and other risk factor data; blood samples for malaria microscopy and stool samples for and other intestinal Helminthes examinations were collected from each participant. STATA 17 was used for analysis. Chi-square and Fishers' exact test were used as required. The internal consistency and model good ness of fitness test were checked using Cronbach's alpha and Hosmer-Lemshow test, respectively. Bivariable and multivariable logistic regression model was used for analysis. Finally, variables with < 0.05, their AOR and their 95% Confidence Intervals were considered statistically significant.
A total of 145 patients with malaria were included in this study of which 11.3% and 49.0% respectively had poly and mono infections. From all malaria confirmed patients, 29.7% were positive for , which was significantly associated with pervious intestinal helminthic infection, history of swimming and fishing participants who lives near to river and having a history of crossing river by their legs without shoe. Moreover, compared with students; farmers merchants and housewives were found to be highly affected.
The co-endemicity of and malaria in the current study was considerably high. Further study is needed to explore the underlying mechanisms of interaction between malaria and with larger sample size.
[寄生虫名称]与疟疾具有相似的流行病学分布或共流行情况。合并感染是一项全球公共卫生负担，流行病学证据对于采取循证干预措施至关重要。因此，本研究的目的是评估埃塞俄比亚东北部疟疾流行地区疟疾阳性患者中[寄生虫名称]与其他肠道蠕虫合并感染的患病率及相关因素。
2018年9月至2019年6月，在埃塞俄比亚东北部的凯米斯和切法罗比特对随机招募的145名经显微镜确诊的疟疾患者进行了一项横断面研究。使用预先测试的半结构化问卷收集社会人口学和其他危险因素数据；从每位参与者采集用于疟疾显微镜检查的血样和用于[寄生虫名称]及其他肠道蠕虫检查的粪便样本。使用STATA 17进行分析。根据需要使用卡方检验和费舍尔精确检验。分别使用克朗巴赫α系数和霍斯默-莱姆肖检验检查内部一致性和模型拟合优度检验。使用双变量和多变量逻辑回归模型进行分析。最后，P<0.05的变量、其调整后比值比（AOR）及其95%置信区间被认为具有统计学意义。
本研究共纳入145例疟疾患者，其中11.3%和49.0%分别患有多重感染和单一感染。在所有确诊的疟疾患者中，29.7%的患者[寄生虫名称]检测呈阳性，这与既往肠道蠕虫感染、游泳史、居住在河流附近且有赤脚过河史的捕鱼参与者显著相关。此外，与学生相比，农民、商人和家庭主妇受影响更大。
在本研究中，[寄生虫名称]与疟疾的共流行程度相当高。需要进一步研究以更大样本量探索疟疾与[寄生虫名称]之间相互作用的潜在机制。
