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成人无明确过敏原的嗜酸性粒细胞性胃肠炎：一例报告

Eosinophilic gastroenteritis without identifiable allergens in an adult: A case report.

作者信息

Lan Haisheng, Yang Tishang, Zhou Li, Lv Jiansheng, Huang Xvsen

机构信息

The First Clinical Medical College of Jinan University, Jinan University, Guangzhou, Guangdong, China.

Department of Gastrointestinal Surgery, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.

出版信息

SAGE Open Med Case Rep. 2025 Feb 3;13:2050313X241312935. doi: 10.1177/2050313X241312935. eCollection 2025.

DOI:10.1177/2050313X241312935
PMID:39906476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11792021/
Abstract

Eosinophilic gastrointestinal is an uncommon disorder affecting all tissues of the digestive tract. Eosinophilic gastroenteritis presents with a complex clinical profile, lacks specificity, and is prone to misdiagnosis in patients without evident allergens. In some instances, it is mistaken for an acute abdomen or a gastrointestinal tumor, potentially leading to unnecessary surgical interventions. We present the case of a 21-year-old female with eosinophilic gastroenteritis whose primary clinical manifestations were abdominal pain and ascites.

摘要

嗜酸性粒细胞性胃肠病是一种影响消化道所有组织的罕见疾病。嗜酸性粒细胞性胃肠炎临床表现复杂，缺乏特异性，在无明显过敏原的患者中容易误诊。在某些情况下，它被误诊为急腹症或胃肠道肿瘤，可能导致不必要的手术干预。我们报告一例21岁嗜酸性粒细胞性胃肠炎女性患者，其主要临床表现为腹痛和腹水。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/e2ef8532a6ae/10.1177_2050313X241312935-fig12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/1a76714771bc/10.1177_2050313X241312935-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/2446e2f8cb82/10.1177_2050313X241312935-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/e6e3e26e0095/10.1177_2050313X241312935-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/47be6b52b6de/10.1177_2050313X241312935-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/c37559077f46/10.1177_2050313X241312935-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/1d46c23b5e07/10.1177_2050313X241312935-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/e1f46d4667d8/10.1177_2050313X241312935-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/3bae90fe3e84/10.1177_2050313X241312935-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/90ec9ec00ddd/10.1177_2050313X241312935-fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/1bef108798c5/10.1177_2050313X241312935-fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/49e534ed67dd/10.1177_2050313X241312935-fig11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/e2ef8532a6ae/10.1177_2050313X241312935-fig12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/1a76714771bc/10.1177_2050313X241312935-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/2446e2f8cb82/10.1177_2050313X241312935-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/e6e3e26e0095/10.1177_2050313X241312935-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/47be6b52b6de/10.1177_2050313X241312935-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/c37559077f46/10.1177_2050313X241312935-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/1d46c23b5e07/10.1177_2050313X241312935-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/e1f46d4667d8/10.1177_2050313X241312935-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/3bae90fe3e84/10.1177_2050313X241312935-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/90ec9ec00ddd/10.1177_2050313X241312935-fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/1bef108798c5/10.1177_2050313X241312935-fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/49e534ed67dd/10.1177_2050313X241312935-fig11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da92/11792021/e2ef8532a6ae/10.1177_2050313X241312935-fig12.jpg

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本文引用的文献

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Eosinophilic gastroenteritis - a manifestation of an allergic disease in the gastrointestinal tract? Part 2. Treatment.嗜酸性粒细胞性胃肠炎——胃肠道过敏性疾病的一种表现？第2部分。治疗
Prz Gastroenterol. 2023;18(2):135-140. doi: 10.5114/pg.2022.118635. Epub 2022 Aug 9.
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Eosinophilic gastroenteritis: Pathogenesis, diagnosis, and treatment.嗜酸性粒细胞性胃肠炎：发病机制、诊断和治疗。
Chin Med J (Engl). 2023 Apr 20;136(8):899-909. doi: 10.1097/CM9.0000000000002511. Epub 2023 Apr 6.
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Eosinophilic Gastrointestinal Diseases: The Pathogenesis, Diagnosis, and Treatment.
嗜酸性粒细胞性胃肠道疾病：发病机制、诊断和治疗。
Intern Med. 2023 Jan 1;62(1):1-10. doi: 10.2169/internalmedicine.8417-21. Epub 2021 Oct 19.
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Less Known Gastrointestinal Manifestations of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: A Systematic Review of the Literature.药物超敏反应伴嗜酸性粒细胞增多和全身症状（DRESS）综合征鲜为人知的胃肠道表现：文献系统综述
J Clin Med. 2021 Sep 21;10(18):4287. doi: 10.3390/jcm10184287.
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with Gastroduodenal Involvement and Complicated with SIADH: An Unusual Diagnosis to Consider in Immunosuppressed Patients with Hyperemesis and Eosinophilia.伴有胃十二指肠受累并合并抗利尿激素分泌异常综合征：免疫抑制且伴有剧烈呕吐和嗜酸性粒细胞增多的患者需考虑的一种罕见诊断。
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Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review.孟鲁司特在嗜酸性粒细胞性胃肠炎中的成功应用：病例报告及文献复习。
BMC Gastroenterol. 2021 Jul 8;21(1):279. doi: 10.1186/s12876-021-01854-x.
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