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嗜酸性粒细胞性胃肠炎的内镜特征及诊断方法

Endoscopic Features and Diagnostic Procedures of Eosinophilic Gastroenteritis.

作者信息

Ashitani Keigo, Tsuzuki Yoshikazu, Yamaoka Minoru, Ohgo Hideki, Ichimura Takaya, Kusano Takeru, Nakayama Tomohiro, Nakamoto Hidetomo, Imaeda Hiroyuki

机构信息

Department of General Internal Medicine, Saitama Medical University, Japan.

Department of Gastroenterology, Saitama Medical University, Japan.

出版信息

Intern Med. 2019 Aug 1;58(15):2167-2171. doi: 10.2169/internalmedicine.2298-18. Epub 2019 Apr 17.

Abstract

No specific endoscopic features for eosinophilic gastroenteritis (EGE) have been reported previously. This study therefore evaluated the endoscopic findings of six patients with EGE. The diagnosis was confirmed based on gastrointestinal symptoms, pathological findings on biopsy, and the absence of other diseases. The site of the lesion was identified based on eosinophilic infiltration with ≥20 cells per high-power field during a pathological specimen analysis. Flattening of the small intestinal villi was observed in four patients; we speculate that this may be a specific feature in the diagnosis of EGE.

摘要

此前尚无关于嗜酸性粒细胞性胃肠炎(EGE)的特定内镜特征的报道。因此,本研究评估了6例EGE患者的内镜检查结果。诊断基于胃肠道症状、活检的病理结果以及排除其他疾病。在病理标本分析中,根据每高倍视野嗜酸性粒细胞浸润≥20个细胞来确定病变部位。4例患者观察到小肠绒毛变平;我们推测这可能是EGE诊断中的一个特定特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc3f/6709335/94956ac1e28f/1349-7235-58-2167-g001.jpg

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