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由寄生虫感染引起的严重症状性低钙血症:一例罕见病例。

Severe symptomatic hypocalcemia due to infestation: A rare case.

作者信息

Ajmal Ali, Chirculescu Camelia, Alyamani Tariq, Hiett Gregory J, Shrestha Dhan Bahadur

机构信息

Division of Endocrinology, Department of Medicine, Joan C. Edwards School of Medicine-Marshall Univeersity, Huntington, West Virginia 25701, USA.

Department of Internal Medicine, Johnston Memorial Hospital, Abingdon, VA 24211-7664, USA.

出版信息

IDCases. 2025 Jan 16;39:e02157. doi: 10.1016/j.idcr.2025.e02157. eCollection 2025.

Abstract

INTRODUCTION

Severe hypocalcemia can affect multiple systems, causing a wide variety of symptoms ranging from muscle weakness to twitching. In severe cases, it can lead to heart rhythm disturbances and seizures. A rare cause of hypocalcemia is due to malabsorption associated with prolonged gastroenteritis.

CASE PRESENTATION

We present a 35-year-old female with persistent watery diarrhea of eight weeks presented with neuromuscular symptoms. Trousseau sign and Chvostek sign were positive bilaterally. Laboratory test results revealed severe hypokalemia, hypocalcemia, and anemia, with prolonged QT interval in electrocardiogram (EKG). Her stool polymerase chain reaction (PCR) revealed . Her electrolytes were appropriately replaced during her hospital stay. The patient was successfully treated with trimethoprim-sulfamethoxazole, calcium, and oral iron supplementation.

CONCLUSION

This case demonstrates a unique presentation of a healthy young female with symptomatic hypocalcemia resulting from malabsorption due to . This case emphasizes the importance of early diagnosis using newer techniques, such as polymerase chain reaction (PCR) for parasite DNA, which can result in appropriate diagnosis and timely treatment.

摘要

引言

严重低钙血症可影响多个系统,引发从肌肉无力到抽搐等各种各样的症状。在严重情况下,可导致心律紊乱和癫痫发作。低钙血症的一个罕见原因是与长期肠胃炎相关的吸收不良。

病例介绍

我们报告一名35岁女性,有持续8周的水样腹泻,并伴有神经肌肉症状。双侧陶瑟征和Chvostek征均呈阳性。实验室检查结果显示严重低钾血症、低钙血症和贫血,心电图(EKG)显示QT间期延长。她的粪便聚合酶链反应(PCR)显示……。住院期间其电解质得到适当补充。该患者通过甲氧苄啶-磺胺甲恶唑、钙剂和口服铁剂补充成功治愈。

结论

本病例展示了一名健康年轻女性因……吸收不良导致有症状性低钙血症的独特表现。该病例强调了使用诸如针对寄生虫DNA的聚合酶链反应(PCR)等新技术进行早期诊断的重要性,这可实现恰当诊断并及时治疗。

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