Perez Giovanny E, Bures Antonio, Melero-Pardo Ana L, Garraton Francisco, Hernández-Herrera Gabriel A, Portela-Arraiza Juan C
Otolaryngology - Head and Neck Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, PRI.
Otolaryngology - Head and Neck Surgery, University of Puerto Rico School of Medicine, San Juan, PRI.
Cureus. 2025 Jan 6;17(1):e77001. doi: 10.7759/cureus.77001. eCollection 2025 Jan.
Chronic maxillary atelectasis (CMA) is characterized by a persistent reduction in maxillary sinus volume, resulting from inward bowing of its antral walls. Silent sinus syndrome (SSS), a rare manifestation of CMA, typically presents with significant bony structural changes but without the usual nasal symptoms. The primary clinical presentation of SSS often includes enophthalmos, which may lead to referrals to ophthalmology due to perceived ocular asymmetry. This case series presents the familial occurrence of CMA and SSS in three male family members, each exhibiting different degrees of nasal symptoms and imaging findings consistent with maxillary sinus opacification and collapse. The familial clustering of these cases suggests a possible genetic or hereditary component to the development of CMA and SSS, an aspect not commonly explored in the existing literature.
慢性上颌窦肺不张(CMA)的特征是上颌窦容积持续减小,这是由其窦壁向内弯曲所致。寂静鼻窦综合征(SSS)是CMA的一种罕见表现,通常表现为明显的骨质结构改变,但无常见的鼻部症状。SSS的主要临床表现常包括眼球内陷,由于察觉到眼部不对称,这可能导致转诊至眼科。本病例系列介绍了三名男性家庭成员中CMA和SSS的家族性发生情况,每个人都表现出不同程度的鼻部症状以及与上颌窦混浊和塌陷一致的影像学表现。这些病例的家族聚集性表明CMA和SSS的发生可能存在遗传或遗传因素,这是现有文献中较少探讨的一个方面。