Stewart Michael G, Witsell David L, Smith Timothy L, Weaver Edward M, Yueh Bevan, Hannley Maureen T
Bobby R Alford Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, TX 77030, USA.
Otolaryngol Head Neck Surg. 2004 Feb;130(2):157-63. doi: 10.1016/j.otohns.2003.09.016.
The study goal was to validate a disease-specific health status instrument for use in patients with nasal obstruction.Design, settings, and patients The study consisted of a prospective instrument validation conducted at 4 academic medical centers with 32 adults with nasal septal deformity.
Prospective instrument validation occurred in 2 stages. Stage 1 was the development of a preliminary (alpha-version) instrument of potential items. Stage 2 was a test of the alpha-version for item performance, internal consistency, and test-retest reliability; construct, discriminant, criterion validity, and responsiveness; and creation of the final instrument.
Items with poor performance were eliminated from the alpha-version instrument. In testing the final instrument, test-retest reliability was adequate at 0.702; internal consistency reliability was also adequate at 0.785. Validity was confirmed using correlation and comparison analysis, and response sensitivity was excellent.
The Nasal Obstruction Symptom Evaluation Scale is a valid, reliable, and responsive instrument that is brief and easy to complete and has potential use for outcomes studies in adults with nasal obstruction.
本研究旨在验证一种针对鼻塞患者的疾病特异性健康状况评估工具。设计、地点和患者：本研究为前瞻性工具验证研究，在4个学术医疗中心对32名鼻中隔畸形的成年人进行。
前瞻性工具验证分两个阶段进行。第一阶段是开发一个包含潜在条目的初步（α版）工具。第二阶段是对α版工具进行条目性能、内部一致性和重测信度测试；结构效度、区分效度、效标效度和反应度测试；并创建最终工具。
性能不佳的条目从α版工具中剔除。在对最终工具进行测试时，重测信度为0.702，足够；内部一致性信度为0.785，也足够。通过相关性和比较分析证实了效度，反应敏感性极佳。
鼻塞症状评估量表是一种有效、可靠且反应灵敏的工具，简短易完成，对成人鼻塞患者的结局研究具有潜在用途。
