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鼻阻塞症状评估(NOSE)量表的制定与验证

Development and validation of the Nasal Obstruction Symptom Evaluation (NOSE) scale.

作者信息

Stewart Michael G, Witsell David L, Smith Timothy L, Weaver Edward M, Yueh Bevan, Hannley Maureen T

机构信息

Bobby R Alford Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Otolaryngol Head Neck Surg. 2004 Feb;130(2):157-63. doi: 10.1016/j.otohns.2003.09.016.

Abstract

OBJECTIVE

The study goal was to validate a disease-specific health status instrument for use in patients with nasal obstruction.Design, settings, and patients The study consisted of a prospective instrument validation conducted at 4 academic medical centers with 32 adults with nasal septal deformity.

METHODS

Prospective instrument validation occurred in 2 stages. Stage 1 was the development of a preliminary (alpha-version) instrument of potential items. Stage 2 was a test of the alpha-version for item performance, internal consistency, and test-retest reliability; construct, discriminant, criterion validity, and responsiveness; and creation of the final instrument.

RESULTS

Items with poor performance were eliminated from the alpha-version instrument. In testing the final instrument, test-retest reliability was adequate at 0.702; internal consistency reliability was also adequate at 0.785. Validity was confirmed using correlation and comparison analysis, and response sensitivity was excellent.

CONCLUSIONS

The Nasal Obstruction Symptom Evaluation Scale is a valid, reliable, and responsive instrument that is brief and easy to complete and has potential use for outcomes studies in adults with nasal obstruction.

摘要

目的

本研究旨在验证一种针对鼻塞患者的疾病特异性健康状况评估工具。设计、地点和患者:本研究为前瞻性工具验证研究,在4个学术医疗中心对32名鼻中隔畸形的成年人进行。

方法

前瞻性工具验证分两个阶段进行。第一阶段是开发一个包含潜在条目的初步(α版)工具。第二阶段是对α版工具进行条目性能、内部一致性和重测信度测试;结构效度、区分效度、效标效度和反应度测试;并创建最终工具。

结果

性能不佳的条目从α版工具中剔除。在对最终工具进行测试时,重测信度为0.702,足够;内部一致性信度为0.785,也足够。通过相关性和比较分析证实了效度,反应敏感性极佳。

结论

鼻塞症状评估量表是一种有效、可靠且反应灵敏的工具,简短易完成,对成人鼻塞患者的结局研究具有潜在用途。

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