Qataya Passant Osama, Zaki Azza Mohamed, Amin Fatma, Swedan Ahmed, Elkafrawy Hagar
Oral Medicine, Periodontology, Radiology and Diagnosis, Department of Oral Medicine, Periodontology, Radiology and Diagnosis, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Clin Oral Investig. 2025 Feb 6;29(2):118. doi: 10.1007/s00784-025-06189-5.
The aim of this clinical trial was to evaluate the effectiveness of Piano level laser therapy using Nd-YAG laser and intramuscular EGF injection in pain alleviation, function, and quality of life improvement in patients suffering from myogenic TMD.
A randomized clinical trial was performed on 29 patients suffering from chronic painful myogenic TMD based on diagnostic criteria for temporomandibular disorders. Group I (n = 13patients) was treated using 1064 nm Nd-YAG Laser (4 sessions once/week). Group II (n = 14 patients) was treated by intramuscular injection of EGF. Pain using numerical rating score, pain free opening and unassisted maximum opening were measured at baseline, 7,14,21 days, 1 and 3 months. Quality of life using OHIP-14 was assessed at baseline, 1 and 3 months.
Results showed that there was a significant pain reduction (P < 0.000) and increase in pain free opening (P < 0.0001) in both test groups. However, only group I showed a significant increase in maximum opening (P = 0.007). Quality of life significantly improved in both groups (P = 0.0001). There was no significant difference between the two treatments in pain scores, pain free opening, maximum opening nor quality of life.
Both treatment modalities offered effective and cost-effective non- to minimally invasive treatment options for myogenic TMD with no side effects.
Myogenic TMD forms a public health issue and is a common musculoskeletal problem causing pain and disability. The proposal of effective, non-invasive, and affordable treatment options can help solve this issue.
本临床试验旨在评估使用钕钇铝石榴石激光(Nd-YAG激光)的Piano水平激光疗法和肌肉注射表皮生长因子(EGF)对缓解肌源性颞下颌关节紊乱病(TMD)患者的疼痛、改善功能和提高生活质量的有效性。
根据颞下颌关节紊乱病的诊断标准,对29例患有慢性疼痛性肌源性TMD的患者进行了一项随机临床试验。第一组(n = 13例患者)使用1064纳米Nd-YAG激光进行治疗(每周一次,共4次)。第二组(n = 14例患者)通过肌肉注射EGF进行治疗。在基线、第7天、14天、21天、1个月和3个月时测量使用数字评分量表的疼痛程度、无痛开口度和无辅助最大开口度。在基线、1个月和3个月时使用口腔健康影响程度量表(OHIP-14)评估生活质量。
结果显示,两个试验组的疼痛均显著减轻(P < 0.000),无痛开口度均增加(P < 0.0001)。然而,只有第一组的最大开口度有显著增加(P = 0.007)。两组的生活质量均显著改善(P = 0.0001)。两种治疗方法在疼痛评分、无痛开口度、最大开口度和生活质量方面均无显著差异。
两种治疗方式都为肌源性TMD提供了有效且经济高效的非侵入性至微创治疗选择,且无副作用。
肌源性TMD是一个公共卫生问题,是导致疼痛和残疾的常见肌肉骨骼问题。提出有效、非侵入性且经济实惠的治疗选择有助于解决这一问题。