Biomedical Science, Hospital das Clínicas de Goiás, Goiânia 74605-020, Brazil.
Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.
Int J Mol Sci. 2024 May 21;25(11):5604. doi: 10.3390/ijms25115604.
Bioproducts derived from platelets have been extensively used across various medical fields, with a recent notable surge in their application in dermatology and aesthetic procedures. These products, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), play crucial roles in inducing blood vessel proliferation through growth factors derived from peripheral blood. PRP and PRF, in particular, facilitate fibrin polymerization, creating a robust structure that serves as a reservoir for numerous growth factors. These factors contribute to tissue regeneration by promoting cell proliferation, differentiation, and migration and collagen/elastin production. Aesthetic medicine harnesses these effects for diverse purposes, including hair restoration, scar treatment, striae management, and wound healing. Furthermore, these biological products can act as adjuvants with other treatment modalities, such as laser therapy, radiofrequency, and microneedling. This review synthesizes the existing evidence, offering insights into the applications and benefits of biological products in aesthetic medicine.
从血小板中提取的生物制品已广泛应用于各个医学领域，最近在皮肤科和美容手术中的应用显著增加。这些产品，如富含血小板的血浆（PRP）和富含血小板的纤维蛋白（PRF），通过外周血中的生长因子在诱导血管增殖方面发挥着关键作用。PRP 和 PRF 特别促进纤维蛋白聚合，形成一个坚固的结构，作为许多生长因子的储存库。这些因子通过促进细胞增殖、分化和迁移以及胶原蛋白/弹性蛋白的产生来促进组织再生。美容医学利用这些作用来实现多种目的，包括头发修复、疤痕治疗、妊娠纹管理和伤口愈合。此外，这些生物制品可以作为其他治疗方式（如激光治疗、射频和微针）的佐剂。本综述综合了现有证据，深入探讨了生物制品在美容医学中的应用和益处。
