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肱骨干骨折髓内钉固定与钢板固定的疗效:一项回顾性队列研究。

Outcomes of intramedullary nailing versus plate fixation for humeral shaft fractures: a retrospective cohort study.

作者信息

Derbas Jawad, Moghamis Isam, Alzobi Osama, Elshoeibi Amgad, Murshid Abdullah, Ahmed Ghalib

机构信息

Department of Orthopedic Surgery, Hamad General Hospital, Doha, Qatar.

College of Medicine, QU Health, Qatar University, Doha, Qatar.

出版信息

Eur J Orthop Surg Traumatol. 2025 Feb 7;35(1):63. doi: 10.1007/s00590-025-04181-z.

Abstract

BACKGROUND

Humeral shaft fractures account for 1-3% of all bone fractures. Conservative treatment often leads to complications such as non-union and shoulder stiffness. Surgical fixation with a dynamic compression plate (DCP) has been the gold standard treatment. Intramedullary nailing (IMN) has recently gained popularity due to its minimally invasive approach and reduced risk of radial nerve injury. This study aims to compare the outcomes of IMN and plate fixation for humeral shaft fractures.

METHODS

This retrospective study included patients with humeral shaft fractures treated with either IMN or DCP fixation at Hamad General Hospital between April 2015 and October 2018. Patient demographics, fracture characteristics, surgical outcomes, and complications were collected. Descriptive statistics were used to summarize patient information, and univariate analysis was conducted to compare both groups. A Cox proportional hazards model, adjusted for age, gender, and polytrauma status was applied to compare time to union between IMN and DCP groups.

RESULTS

Sixty five patients (25 IMN, 40 plate fixation) were included. Non-union rates were higher in the DCP group than in the IMN group (13% vs. 4%). Reoperation rates were also higher in the DCP group (20% vs. 4%). Postoperative neuropathy rates were 4% for IMN and 10% for DCP, with neuropathy resolution significantly higher in the IMN group (92% vs. 68%). Shoulder range of motion (ROM) and pain favored the DCP group, with 98% unaffected ROM in the plate group compared to 76% in the IMN group (p = 0.007), and a lower incidence of shoulder pain (28% vs. 98%, p < 0.001). Time to union was comparable between both groups, with an adjusted hazard ratio of 1.08 (95% CI 0.62-1.90; p = 0.776).

CONCLUSION

IMN and plate fixation effectively achieved fracture union; however, plate fixation was associated with better shoulder function, reduced pain, and higher reoperation rates. IMN was linked to a lower risk of nerve injury but compromised shoulder ROM and resulted in more postoperative pain.

摘要

背景

肱骨干骨折占所有骨折的1%-3%。保守治疗常导致诸如骨不连和肩关节僵硬等并发症。使用动力加压钢板(DCP)进行手术固定一直是金标准治疗方法。髓内钉固定(IMN)因其微创方法和降低的桡神经损伤风险,近年来受到欢迎。本研究旨在比较IMN和钢板固定治疗肱骨干骨折的疗效。

方法

这项回顾性研究纳入了2015年4月至2018年10月期间在哈马德总医院接受IMN或DCP固定治疗的肱骨干骨折患者。收集了患者的人口统计学资料、骨折特征、手术结果和并发症。使用描述性统计来总结患者信息,并进行单因素分析以比较两组。应用经年龄、性别和多发伤状态调整的Cox比例风险模型来比较IMN组和DCP组的骨愈合时间。

结果

共纳入65例患者(25例IMN,40例钢板固定)。DCP组的骨不连发生率高于IMN组(13%对4%)。DCP组的再次手术率也更高(20%对4%)。IMN术后神经病变发生率为4%,DCP为10%,IMN组神经病变缓解率显著更高(92%对68%)。肩关节活动范围(ROM)和疼痛方面DCP组更具优势,钢板组98%的ROM未受影响,而IMN组为76%(p = 0.007),且肩关节疼痛发生率更低(28%对98%,p < 0.001)。两组的骨愈合时间相当(调整后的风险比为1.08;95%可信区间为0.62 - 1.90;p = 0.776)。

结论

IMN和钢板固定均能有效实现骨折愈合;然而,钢板固定与更好的肩关节功能、减轻疼痛和更高的再次手术率相关联;IMN与较低的神经损伤风险相关,但损害了肩关节ROM并导致更多的术后疼痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d71d/11802612/3190ad27b245/590_2025_4181_Fig1_HTML.jpg

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