Yu Hannah J, Choi Sophia, Guiseppi Rodney, Banaee Touka
John Sealy School of Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Department of Ophthalmology and Visual Sciences, University of Texas. Medical Branch, Galveston, Texas, USA.
J Ophthalmic Vis Res. 2024 Dec 31;19(4):488-507. doi: 10.18502/jovr.v19i4.16559. eCollection 2024 Dec.
Retinal artery occlusion (RAO) is a well-characterized ischemic ophthalmic event that may result in sudden and devastating vision loss. The etiology of RAO may vary including both arteritic and non-arteritic causes and the location of the lesion can extend from the ophthalmic artery to the branches of the central retinal artery. Given this variable causes of RAO, the clinical presentation and extent of vision loss may also differ from case to case, necessitating a prompt and thorough evaluation, including a full stroke work up. While there is currently no widely accepted standard for the treatment of RAO, there are several proposed methods that have been or are currently being investigated through retrospective studies and prospective trials. The current article aims to provide a review of the pathophysiology, clinical presentation, and management of RAO in addition to presenting a systematic review of recently published studies on treatment options for RAO.
视网膜动脉阻塞(RAO)是一种特征明确的缺血性眼科疾病,可导致突然且严重的视力丧失。RAO的病因可能多种多样,包括动脉炎性和非动脉炎性原因,病变位置可从眼动脉延伸至视网膜中央动脉的分支。鉴于RAO病因的多样性,其临床表现和视力丧失程度也可能因病例而异,因此需要进行迅速而全面的评估,包括全面的卒中检查。虽然目前尚无被广泛接受的RAO治疗标准,但有几种已提出的方法已经或正在通过回顾性研究和前瞻性试验进行研究。本文旨在综述RAO的病理生理学、临床表现和治疗,此外还将对最近发表的关于RAO治疗方案的研究进行系统综述。