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视网膜动脉阻塞:当前治疗方法综述

Retinal Artery Occlusion: A Review of Current Management Practices.

作者信息

Yu Hannah J, Choi Sophia, Guiseppi Rodney, Banaee Touka

机构信息

John Sealy School of Medicine, University of Texas Medical Branch, Galveston, Texas, USA.

Department of Ophthalmology and Visual Sciences, University of Texas. Medical Branch, Galveston, Texas, USA.

出版信息

J Ophthalmic Vis Res. 2024 Dec 31;19(4):488-507. doi: 10.18502/jovr.v19i4.16559. eCollection 2024 Dec.

DOI:10.18502/jovr.v19i4.16559
PMID:39917461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11795002/
Abstract

Retinal artery occlusion (RAO) is a well-characterized ischemic ophthalmic event that may result in sudden and devastating vision loss. The etiology of RAO may vary including both arteritic and non-arteritic causes and the location of the lesion can extend from the ophthalmic artery to the branches of the central retinal artery. Given this variable causes of RAO, the clinical presentation and extent of vision loss may also differ from case to case, necessitating a prompt and thorough evaluation, including a full stroke work up. While there is currently no widely accepted standard for the treatment of RAO, there are several proposed methods that have been or are currently being investigated through retrospective studies and prospective trials. The current article aims to provide a review of the pathophysiology, clinical presentation, and management of RAO in addition to presenting a systematic review of recently published studies on treatment options for RAO.

摘要

视网膜动脉阻塞(RAO)是一种特征明确的缺血性眼科疾病,可导致突然且严重的视力丧失。RAO的病因可能多种多样,包括动脉炎性和非动脉炎性原因,病变位置可从眼动脉延伸至视网膜中央动脉的分支。鉴于RAO病因的多样性,其临床表现和视力丧失程度也可能因病例而异,因此需要进行迅速而全面的评估,包括全面的卒中检查。虽然目前尚无被广泛接受的RAO治疗标准,但有几种已提出的方法已经或正在通过回顾性研究和前瞻性试验进行研究。本文旨在综述RAO的病理生理学、临床表现和治疗,此外还将对最近发表的关于RAO治疗方案的研究进行系统综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/ff9829854dd2/jovr-19-488-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/903e9158a0d3/jovr-19-488-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/9a46fe1ddc40/jovr-19-488-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/95bf97bed3b8/jovr-19-488-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/98ea8ef77516/jovr-19-488-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/a2a813624155/jovr-19-488-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/ff9829854dd2/jovr-19-488-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/903e9158a0d3/jovr-19-488-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/9a46fe1ddc40/jovr-19-488-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/95bf97bed3b8/jovr-19-488-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/98ea8ef77516/jovr-19-488-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/a2a813624155/jovr-19-488-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c35/11795002/ff9829854dd2/jovr-19-488-g006.jpg

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本文引用的文献

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OCTA characteristics in non-arteritic central retinal artery occlusion and correlation with visual acuity.非动脉炎性视网膜中央动脉阻塞的光学相干断层扫描血管造影特征及其与视力的相关性
Int J Ophthalmol. 2024 Feb 18;17(2):289-296. doi: 10.18240/ijo.2024.02.10. eCollection 2024.
2
Atrial fibrillation as a novel risk factor for retinal stroke: A protocol for a population-based retrospective cohort study.心房颤动作为视网膜卒中的新危险因素:一项基于人群的回顾性队列研究方案。
PLoS One. 2023 Dec 29;18(12):e0296251. doi: 10.1371/journal.pone.0296251. eCollection 2023.
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Central Retinal Artery Occlusion: Visual Outcomes from a Large Northern California Cohort.
Med Biol Eng Comput. 2025 Mar 31. doi: 10.1007/s11517-025-03353-7.
中心性视网膜动脉阻塞:来自加利福尼亚北部大型队列的视觉预后结果。
Ophthalmol Retina. 2024 Jun;8(6):566-570. doi: 10.1016/j.oret.2023.12.007. Epub 2023 Dec 27.
4
Long-term outcomes of intravenous fibrinolysis in central retinal artery occlusion.视网膜中央动脉阻塞静脉内溶栓的长期疗效。
Sci Rep. 2023 Nov 22;13(1):20505. doi: 10.1038/s41598-023-47987-9.
5
Risk of Stroke, Myocardial Infarction, and Death After Retinal Artery Occlusion.视网膜动脉阻塞后中风、心肌梗死和死亡的风险。
JAMA Ophthalmol. 2023 Dec 1;141(12):1110-1116. doi: 10.1001/jamaophthalmol.2023.4716.
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Efficacy and safety of hyperbaric oxygen therapy monitored by fluorescein angiography in patients with retinal artery occlusion.荧光素眼底血管造影监测高压氧治疗视网膜动脉阻塞的疗效及安全性。
Br J Ophthalmol. 2024 Jun 20;108(7):956-962. doi: 10.1136/bjo-2023-323972.
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Quantitative Wide-Field Swept-Source Optical Coherence Tomography Angiography and Visual Outcomes in RAO.视网膜中央动脉阻塞(RAO)的定量广角扫频光学相干断层扫描血管造影及视觉预后
Clin Ophthalmol. 2023 Aug 22;17:2505-2513. doi: 10.2147/OPTH.S418370. eCollection 2023.
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Safety and effectiveness of IV Thrombolysis in retinal artery occlusion: A multicenter retrospective cohort study.视网膜动脉阻塞中 IV 溶栓的安全性和有效性:一项多中心回顾性队列研究。
Eur Stroke J. 2023 Dec;8(4):966-973. doi: 10.1177/23969873231185895. Epub 2023 Jul 7.
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Optical Coherence Tomography Angiography in Retinal Vascular Disorders.视网膜血管疾病中的光学相干断层扫描血管造影术
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