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Understanding the mechanisms of actions of hydrolytic enzymes in the immunopathogenesis of psoriasis and their inhibitors as treatment options.

作者信息

Bharatha Madeva, Nandana Manuganahalli B, Vishwanath Bannikuppe S, Rajaiah Rajesh

机构信息

Department of Studies in Biochemistry, University of Mysore, Manasagangothri, Mysore, Karnataka, 570006, India.

Department of Studies in Molecular Biology, University of Mysore, Manasagangothri, Mysore, Karnataka, 570006, India.

出版信息

Arch Dermatol Res. 2025 Feb 7;317(1):357. doi: 10.1007/s00403-025-03878-9.

DOI:10.1007/s00403-025-03878-9
PMID:39918641
Abstract
摘要

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本文引用的文献

1
Unconjugated bilirubin and its derivative ameliorate IMQ-induced psoriasis-like skin inflammation in mice by inhibiting MMP9 and MAPK pathway.未结合胆红素及其衍生物通过抑制 MMP9 和 MAPK 通路改善咪喹莫特诱导的小鼠银屑病样皮肤炎症。
Int Immunopharmacol. 2024 Mar 30;130:111679. doi: 10.1016/j.intimp.2024.111679. Epub 2024 Feb 20.
2
Matrix metalloproteinase-7 could be a predictor for acute inflammation in psoriatic patients.基质金属蛋白酶-7 可能是银屑病患者急性炎症的预测因子。
Cytokine. 2020 Oct;134:155195. doi: 10.1016/j.cyto.2020.155195. Epub 2020 Jul 11.
3
A Review of the Use of Secukinumab for Psoriatic Arthritis.
司库奇尤单抗用于银屑病关节炎的应用综述
Rheumatol Ther. 2017 Dec;4(2):233-246. doi: 10.1007/s40744-017-0076-0. Epub 2017 Aug 28.
4
The Exonuclease Trex2 Shapes Psoriatic Phenotype.外切核酸酶Trex2塑造银屑病表型。
J Invest Dermatol. 2016 Dec;136(12):2345-2355. doi: 10.1016/j.jid.2016.05.122. Epub 2016 Jun 27.
5
Psoriasis.银屑病
N Engl J Med. 2009 Jul 30;361(5):496-509. doi: 10.1056/NEJMra0804595.