Organophosphate ester flame retardants in sediments and marine fish species in Colombia: Occurrence, distribution, and implications for human risk assessment.

Exposure to organophosphate esters (OPEs) remains a significant concern, especially in aquatic systems where these compounds can bioaccumulate in organisms. However, limited information exists regarding their potential health risks to humans through the food web in tropical ecosystems. This study investigated the levels, bioaccumulation, and trophic transfer of OPEs in sediments and marine fish species from Cartagena and Barbacoas bays, Colombia. Twenty target OPEs were quantified in sediments and fish. The average concentrations of ∑OPEs in sediments ranged from 2.80 to 115 ng/g dry weight (dw), while ∑OPE concentrations in fish ranged from 212 to 1968 ng/g lipid weight (lw), with the highest concentrations found in carnivorous species. Trophic magnification factors (TMF) for OPEs varied from 11.0 to 25.8 for compounds such as 2-ethylhexyl diphenyl phosphate (EHDPP), 4-isopropylphenyl diphenyl phosphate (4IPPDPP), tris(2-isopropylphenyl) phosphate (T2IPPP), and tricresylphosphate (TCP), indicating their potential for biomagnification within the marine food web. Biota-sediment accumulation factors (BSAF) for ∑OPEs ranged from 0.340 to 4.32, showing a significant Spearman correlation with log Kow in fish: Pargo chino (r = -0.78, p < 0.05), Mojarra blanca (r = 0.79, p < 0.05), and Lisa (r = 0.72, p < 0.05). This suggests that bioaccumulation and biomagnification of certain OPEs in fish increase with the lipophilicity of these compounds. Despite these findings, the potential human health risk from OPE exposure via fish consumption was found to be minimal.