Department of Anesthesiology, School of Medicine, Shanghai Putuo People's Hospital, Tongji University, Shanghai, China.
Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Huangpu District, No.639 Zhizaoju Road, Shanghai, 200011, China.
J Headache Pain. 2024 Aug 12;25(1):131. doi: 10.1186/s10194-024-01832-0.
Migraine, a widespread neurological condition, substantially affects the quality of life, particularly for adolescents and young adults. While its impact is significant, there remains a paucity of comprehensive global research on the burden of migraine in younger demographics. Our study sought to elucidate the global prevalence, incidence, and disability-adjusted life-years (DALYs) associated with migraine in the 15-39 age group from 1990 to 2021, utilizing data from the Global Burden of Disease (GBD) 2021 study.
Our comprehensive study analyzed migraine data from the GBD 2021 report, examining the prevalence, incidence, and DALYs across 204 countries and territories over a 32-year span. We stratified the information by age, sex, year, geographical region, and Socio-demographic Index (SDI). To evaluate temporal trends in these metrics, we employed the estimated annual percentage change (EAPC) calculation.
Between 1990 and 2021, the worldwide prevalence of migraine among 15-39 year-olds increased substantially. By 2021, an estimated 593.8 million cases were reported, representing a 39.52% rise from 425.6 million cases in 1990. Global trends showed increases in age-standardized prevalence rate, incidence rate, and DALY rate for migraine during this period. The EAPC were positive for all three metrics: 0.09 for ASPR, 0.03 for ASIR, and 0.09 for DALY rate. Regions with medium SDI reported the highest absolute numbers of prevalent cases, incident cases, and DALYs in 2021. However, high SDI regions demonstrated the most elevated rates overall. Across the globe, migraine prevalence peaked in the 35-39 age group. Notably, female rates consistently exceeded male rates across all age categories.
The global impact of migraine on youths and young adults has grown considerably from 1990 to 2021, revealing notable variations across SDI regions, countries, age groups, and sexes. This escalating burden necessitates targeted interventions and public health initiatives, especially in areas and populations disproportionately affected by migraine.
偏头痛是一种广泛存在的神经系统疾病，极大地影响了生活质量，尤其是青少年和年轻成年人。尽管其影响显著，但目前全球范围内针对年轻人群偏头痛负担的综合研究仍然较少。我们的研究旨在利用 2021 年全球疾病负担（GBD）研究的数据，阐明 1990 年至 2021 年间 15-39 岁人群偏头痛的全球患病率、发病率和残疾调整生命年（DALY）。
我们的综合研究分析了 GBD 2021 报告中的偏头痛数据，在 32 年的时间跨度内，对 204 个国家和地区的患病率、发病率和 DALY 进行了分析。我们按年龄、性别、年份、地理位置和社会人口指数（SDI）对信息进行了分层。为了评估这些指标的时间趋势，我们采用了估计年度百分比变化（EAPC）的计算方法。
1990 年至 2021 年间，全球 15-39 岁人群偏头痛的患病率大幅上升。到 2021 年，据估计有 5.938 亿例病例，比 1990 年的 4.256 亿例增加了 39.52%。在这一时期，全球趋势显示偏头痛的年龄标准化患病率、发病率和 DALY 率都有所增加。所有三个指标的 EAPC 均为正值：ASPR 为 0.09，ASIR 为 0.03，DALY 率为 0.09。中 SDI 地区在 2021 年报告了最多的现有病例、发病病例和 DALY。然而，高 SDI 地区的总体发病率最高。在全球范围内，偏头痛的患病率在 35-39 岁年龄组达到峰值。值得注意的是，在所有年龄段中，女性发病率均高于男性。
1990 年至 2021 年间，偏头痛对青少年和年轻成年人的全球影响显著增加，不同 SDI 地区、国家、年龄组和性别之间存在显著差异。这种不断增加的负担需要有针对性的干预措施和公共卫生举措，特别是在受偏头痛影响不成比例的地区和人群中。
