Jiang Cheng, Choi Seok, Gong Hongyang
Department of Cardiology, Shenzhen People's Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, China; Institute of Health Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.
Department of Physiology, College of Medicine, Chosun University, Gwangju, Republic of Korea.
J Psychiatr Res. 2025 Mar;183:31-38. doi: 10.1016/j.jpsychires.2025.02.006. Epub 2025 Feb 5.
Depression is a growing public health concern, and the modest efficacy of current treatments has led to efforts to identify modifiable risk factors. Many nutritional and dietary patterns are linked to depression. The Planetary Health Diet Index (PHDI) measures adherence to sustainable dietary guidelines by the EAT-Lancet Commission. However, the relationship between PHDI and depression has not been studied. This study evaluates this relationship using data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018.
Multivariate logistic regression and weighted quantile sum (WQS) regressions examined the relationship between PHDI, single nutrients, and depression. A generalized additive model with a smoothing plot analyzed the dose-response relationship.
Among 30,446 participants, the highest quartile of PHDI was linked to a reduced risk of depression. WQS analyses showed consistent associations (OR = 0.71, 95%CI: 0.66, 0.76), with Vitamin C, Fiber, and Selenium significant factors. The dose-response curve indicated a linear association between PHDI and depression, with higher PHDI associated with lower depression risk.
The results of this study show a strong negative correlation between PHDI and depression.
抑郁症是一个日益受到关注的公共卫生问题，当前治疗方法的疗效有限，促使人们努力寻找可改变的风险因素。许多营养和饮食模式与抑郁症有关。行星健康饮食指数（PHDI）衡量对EAT-柳叶刀委员会可持续饮食指南的遵循程度。然而，PHDI与抑郁症之间的关系尚未得到研究。本研究使用2007年至2018年美国国家健康与营养检查调查（NHANES）的数据评估这种关系。
多变量逻辑回归和加权分位数和（WQS）回归分析了PHDI、单一营养素与抑郁症之间的关系。带有平滑图的广义相加模型分析了剂量反应关系。
在30446名参与者中，PHDI最高四分位数与抑郁症风险降低相关。WQS分析显示出一致的关联（OR = 0.71，95%CI：0.66，0.76），维生素C、纤维和硒是显著因素。剂量反应曲线表明PHDI与抑郁症之间存在线性关联，PHDI越高，抑郁症风险越低。
本研究结果表明PHDI与抑郁症之间存在强烈的负相关。
