Crile G, Pontius K I, Hawk W A
Surg Gynecol Obstet. 1985 May;160(5):409-13.
Between 1948 and 1977, 84 patients with follicular carcinoma of the thyroid gland were treated at the Cleveland Clinic. The crude survival rate was 73 per cent at five years and 43 per cent at ten years. The most important prognostic factor was the age of the patient--86 per cent of those less then 40 years old appeared to be cured of carcinoma compared with only 26 per cent of those more than 60 years old. The survival of women was a little better than that of men. Patients with large tumors did not do as well as those with small or medium sized ones. Those with highly invasive carcinoma did poorly as did those with oxyphilic tumors. Neither the extent of the operation nor the use of either external radiation or 131I appeared to affect prognosis. Both involvement of lymph nodes and local recurrences had grave prognostic significance. Those who had neither distant metastases nor a history of recurrence after a previous operation when they were first seen by us had good prognoses, 90 per cent of them apparently having been cured.
1948年至1977年间，克利夫兰诊所共治疗了84例甲状腺滤泡癌患者。5年粗生存率为73%，10年为43%。最重要的预后因素是患者的年龄——40岁以下患者中86%的人似乎癌症已治愈，而60岁以上患者中只有26%。女性的生存率略高于男性。肿瘤大的患者预后不如肿瘤小或中等大小的患者。高侵袭性癌患者和嗜酸细胞瘤患者预后较差。手术范围、外照射或131I的使用似乎均不影响预后。淋巴结受累和局部复发均具有严重的预后意义。初次就诊时既无远处转移也无既往手术史的患者预后良好，其中90%的人显然已治愈。
