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青年寻常痤疮患者的生活状况:使用皮肤病生活质量指数(DLQI)对其对生活质量影响的全面考察

Living With Acne Vulgaris in Young Adults: A Holistic Examination of Its Impact on Quality of Life Using the Dermatology Life Quality Index (DLQI).

作者信息

Veldi Venkata Dileep Kumar, Metta Arun Kumar, Metta Sandhya, Angara Sri Sai Praneeth, Teja Peela Anirudh Srinivas, Ponnada Sarath Chandra

机构信息

Medicine, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, IND.

Dermatology, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, IND.

出版信息

Cureus. 2025 Jan 8;17(1):e77167. doi: 10.7759/cureus.77167. eCollection 2025 Jan.

Abstract

BACKGROUND

Acne vulgaris is an inflammatory skin disease that shows chronic effects in adolescents and young adults. Its impact on quality of life (QoL) often extends beyond the physical symptoms, influencing social interactions and reducing self-confidence. Although these impacts are widely acknowledged, they are seldom given sufficient attention or assessed in depth with standardized measures like the Dermatology Life Quality Index (DLQI). This study aimed to evaluate the extent to which acne interferes with QoL in young adults using DLQI scores and its associations with demographic and clinical factors.

METHODS

This hospital-based, cross-sectional study was conducted between October 2023 and December 2023 at Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, India. The study population comprised 200 participants aged 16-28 diagnosed with acne. Data collected included demographic factors (age, sex), clinical features (acne grade, duration, site, scars, hyperpigmentation, and skin type), and DLQI scores. Acne severity was classified from grade I to IV, and the relationships between DLQI scores and clinical/demographic variables were analyzed using chi-squared tests, with statistical significance set at p<0.05. Data analysis was performed using IBM SPSS Statistics for Windows, Version 26.0 (Released 2019; IBM Corp., Armonk, New York, United States).

RESULTS

The mean age of participants was 19.6 years, with women comprising 68.5% of the study population. Acne grade II was the most common, and the average DLQI score was 11.14, indicating a noticeable impact on QoL. Nearly half of the participants (48%) reported a "very large" effect on QoL. Highly significant associations were found between duration of acne, post-acne hyperpigmentation, and grade of acne with DLQI scores (all p<0.001), showing that longer duration, hyperpigmentation, and higher grades of acne significantly worsened QoL. Significant associations were also observed for site of acne and acne scars (both p<0.05), with multiple acne sites and severe scarring linked to greater negative impacts on DLQI scores. Grade III-IV acne were especially tied to bigger hits on QoL. Additionally, site of acne and acne scars were highly associated with acne grade (p<0.001). Factors such as having acne for over two years, oily skin, acne across multiple sites (face, chest, and back), and post-acne hyperpigmentation contributed to higher DLQI scores.

CONCLUSION

Acne vulgaris has a marked impact on QoL in young adults, especially those with severe, persistent, and extensive cases. Focusing on both the physical and mental aspects of acne in treatment could make a difference. Further multi-center studies with larger samples are recommended to generalize these findings and help create targeted interventions.

摘要

背景

寻常痤疮是一种炎症性皮肤病,对青少年和青年具有慢性影响。其对生活质量(QoL)的影响通常不仅限于身体症状,还会影响社交互动并降低自信心。尽管这些影响已得到广泛认可,但很少得到足够的关注,也很少使用皮肤病生活质量指数(DLQI)等标准化措施进行深入评估。本研究旨在使用DLQI评分评估痤疮对青年生活质量的干扰程度及其与人口统计学和临床因素的关联。

方法

本基于医院的横断面研究于2023年10月至2023年12月在印度维沙卡帕特南的加雅特里维迪亚帕里沙德卫生保健与医学技术研究所进行。研究人群包括200名年龄在16 - 28岁被诊断为痤疮的参与者。收集的数据包括人口统计学因素(年龄、性别)、临床特征(痤疮分级、病程、部位、瘢痕、色素沉着和皮肤类型)以及DLQI评分。痤疮严重程度分为I至IV级,使用卡方检验分析DLQI评分与临床/人口统计学变量之间的关系,设定统计学显著性为p<0.05。使用IBM SPSS Statistics for Windows,版本26.0(2019年发布;IBM公司,美国纽约州阿蒙克)进行数据分析。

结果

参与者的平均年龄为19.6岁,女性占研究人群的68.5%。II级痤疮最为常见,平均DLQI评分为11.14,表明对生活质量有显著影响。近一半的参与者(48%)报告对生活质量有“非常大”的影响。发现痤疮病程、痤疮后色素沉着和痤疮分级与DLQI评分之间存在高度显著的关联(均p<0.001),表明病程更长、色素沉着和痤疮分级更高会显著恶化生活质量。痤疮部位和痤疮瘢痕也观察到显著关联(均p<0.05),多个痤疮部位和严重瘢痕与DLQI评分的更大负面影响相关。III - IV级痤疮尤其与对生活质量的更大影响相关。此外,痤疮部位和痤疮瘢痕与痤疮分级高度相关(p<0.001)。痤疮病程超过两年、油性皮肤、多个部位(面部、胸部和背部)出现痤疮以及痤疮后色素沉着等因素导致更高的DLQI评分。

结论

寻常痤疮对青年的生活质量有显著影响,尤其是那些患有严重、持续和广泛病例的患者。在治疗中关注痤疮的身心方面可能会有所不同。建议进行进一步的多中心大样本研究以推广这些发现并帮助制定针对性的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8799/11806962/e2caae095f4a/cureus-0017-00000077167-i01.jpg

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