A Retrospective Study on the Incidence of Kaposi Sarcoma in the United States From 1999 to 2020 Using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research (CDC WONDER) Database.

Introduction Studying cancer incidence is important to understand the cancer risk factors, tracking trends, planning resources and developing prevention and treatment methods. Examining the incidence of Kaposi sarcoma (KS) alongside different variables enables researchers to gain insights into the disease's underlying causes and risk factors. This understanding aids in developing more focused research and interventions. Methodology A retrospective study was conducted using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research (CDC WONDER) database. Data were extracted on July 31, 2024. Incidence of cancer was studied based on the following variables: age, gender, race and geographic location. Results This study describes the demographic characteristics of KS patients in the United States between 1999 and 2020 based on age, gender, and race. Based on age and gender, the crude rate per 1,00,000 was highest initially in ages 75 and above and the male gender. Based on race, the crude rate per 1,00,000 was highest in the Black or African American race. Based on the state, the incidence of KS was highest in California state, followed by New York, and based on the year, the incidence of KS was highest in 2000. Conclusions Incidence in the 35-44 years age group has shown a significant decreasing trend from 2001 to 2020. Other age groups have not shown an evident decreasing or increasing trend over the years. A decreasing trend was observed in White and Black or African American populations, and stable in Asian or Pacific Islander populations, and other races and unknown combined populations.