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儿童无症状颈部肿块与胸腺的正常变异:沙特阿拉伯利雅得一家三级医院的两例报告。

Asymptomatic neck mass and normal variations of the thymus in children: A report of two cases from a tertiary hospital in Riyadh, Saudi Arabia.

作者信息

Albaqami Maryam, Almonifi Abdulaziz, Albelali Areej

机构信息

Departement of Pediatrics, King Abdullah Specialized Children's Hospital, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

出版信息

Ann Thorac Med. 2025 Jan-Mar;20(1):71-73. doi: 10.4103/atm.atm_91_24. Epub 2025 Jan 11.

DOI:10.4103/atm.atm_91_24
PMID:39926397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11804956/
Abstract

The pathogenesis of cervical extension of the thymus has been postulated to be incomplete descent of the thymus in the midline of the neck, which is considered normal in children. The thymus normally extends to the neck in approximately two-thirds of children. Ectopic thymus mainly occurs in 1%-13% of the younger population. In this study, we report two cases of asymptomatic neck swelling, one due to cervical extension of the thymus and the other due to a right submandibular ectopic thymus. None of the patients required any intervention. Recurrent suprasternal swelling in children that becomes more pronounced during coughing/crying or Valsalva maneuvers can be more accurately diagnosed using neck ultrasonography and/or magnetic resonance imaging.

摘要

胸腺向颈部延伸的发病机制被认为是胸腺在颈部中线下降不完全,这在儿童中被视为正常情况。正常情况下,约三分之二的儿童胸腺会延伸至颈部。异位胸腺主要发生在1% - 13%的年轻人群中。在本研究中,我们报告了两例无症状颈部肿胀病例,一例是由于胸腺向颈部延伸,另一例是由于右侧颌下异位胸腺。两名患者均无需任何干预。对于儿童反复出现的胸骨上窝肿胀,在咳嗽/哭闹或瓦尔萨尔瓦动作时更为明显,使用颈部超声和/或磁共振成像可以更准确地进行诊断。

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1
Asymptomatic neck mass and normal variations of the thymus in children: A report of two cases from a tertiary hospital in Riyadh, Saudi Arabia.儿童无症状颈部肿块与胸腺的正常变异:沙特阿拉伯利雅得一家三级医院的两例报告。
Ann Thorac Med. 2025 Jan-Mar;20(1):71-73. doi: 10.4103/atm.atm_91_24. Epub 2025 Jan 11.
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本文引用的文献

1
Prevalence of cervical extension of the thymus in children.儿童胸腺颈部延伸的患病率。
Ann Med Surg (Lond). 2022 Mar 14;76:103483. doi: 10.1016/j.amsu.2022.103483. eCollection 2022 Apr.
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Cervical Extension of the Normal Thymus in Children and Adolescents: Sonographic Features and Prevalence.儿童和青少年正常胸腺的颈椎延伸:超声特征和患病率。
J Ultrasound Med. 2021 Nov;40(11):2361-2367. doi: 10.1002/jum.15619. Epub 2021 Jan 25.
3
Ectopic cervical thymus in children: Clinical and radiographic features.儿童异位颈胸腺:临床和影像学特征。
Laryngoscope. 2020 Jun;130(6):1577-1582. doi: 10.1002/lary.28248. Epub 2019 Aug 28.
4
The inflatable thymus herniation of the normal mediastinal thymus: A case report and review of the literature.正常纵隔胸腺的充气性胸腺疝:一例报告并文献复习
Int J Pediatr Otorhinolaryngol. 2016 Apr;83:74-7. doi: 10.1016/j.ijporl.2016.01.019. Epub 2016 Jan 28.
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Unusual Cause of Suprasternal Swelling: Cervical Extension with Herniation of Mediastinal Thymus.
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Superior cervical extension of the thymus: a normal finding that should not be mistaken for a mass.胸腺颈上延伸:一种正常表现,不应误诊为肿块。
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