Ouellette R D, Blute R, Jaffee S, Bahde C
Urology. 1985 May;25(5):490-1. doi: 10.1016/0090-4295(85)90457-1.
Plasma concentrations of lidocaine were measured over a period of three hours following the instillation of lidocaine jelly (Xylocaine 2% Jelly) into the genitourinary tract of 30 patients (15 male, 15 female) scheduled for cystoscopy. The mean quantity of jelly instilled was 21.4 Gm (11-27.5 Gm) and of lidocaine HCl administered thereby 428 mg (218-550 mg). Plasma concentration reached measurable levels in only 5 cases, never exceeding 0.2 microgram/ml.
对30例计划进行膀胱镜检查的患者（15例男性，15例女性）在泌尿生殖道内注入利多卡因凝胶（赛罗卡因2%凝胶）后三小时内测定血浆利多卡因浓度。注入凝胶的平均量为21.4克（11 - 27.5克），由此给予的盐酸利多卡因平均量为428毫克（218 - 550毫克）。血浆浓度仅在5例中达到可测量水平，从未超过0.2微克/毫升。
