Marquez David X, Tellez Mariana, Ocampo-Mota Jocelyn, Jaldin Michelle A, Hughes Susan, Ajilore Olusola, Chen Jinsong, Walton Surrey, Muramatsu Naoko
Department of Kinesiology and Nutrition, University of Illinois Chicago (UIC), 1919 W. Taylor Street, Room 650, Chicago, IL, 60612, USA.
School of Public Health, University of Illinois Chicago (UIC), 1603 W. Taylor Street, Room 685, Chicago, IL, 60612, USA.
Contemp Clin Trials Commun. 2025 Jan 21;44:101436. doi: 10.1016/j.conctc.2025.101436. eCollection 2025 Apr.
The growing Latino population is 1.5 times more likely to develop Alzheimer's Disease (AD) and Related Dementias (ADRD) than non-Latino Whites. Interventions that can reduce the risk of ADRD are needed. Older Latinos face many barriers to the incorporation of physical activity (PA) into their daily lives given a lack social support, caregiving responsibilities, and lacking resources to maintain PA. Walking and dancing are the two most frequently reported forms of PA among older Latinos, and indoor PA programs conducted in a community location or at home can overcome barriers to participation.
C.E.R.E.B.R.O. (Cognitive Enhancement and Risk-reduction through Exercise for Brain-Related Outcomes; meaning "brain" in English) is testing two remote intervention programs, the BAILAMOS™ dance program and ¡En Forma y Fuerte! (Fit & Strong!), a PA/behavior change program. Participants are randomly assigned to either study condition. The BAILAMOS™ dance program is a 6-month long dance program, in which participants learn different Latin dances including Merengue, Cha Cha Cha, Bachata, Salsa, Cumbia, and Kizomba. Trained CEREBRO staff also lead monthly discussions. Persons randomized to the 3-month long ¡En Forma y Fuerte! program participate in flexibility and aerobic exercise, strength training, and health education. All classes are held live via Zoom. Trained study staff assist participants with technology-related issues. Data are collected through remote testing at baseline, 12 weeks, and 24 weeks after the start of the interventions. Outcomes include PA, cognition, quality of life, social connectedness, and cost-effectiveness.
CEREBRO has the potential to provide evidence regarding the advantages of providing remote intervention programs to reduce PA barriers in the older Latino community.
与非拉丁裔白人相比，不断增长的拉丁裔人口患阿尔茨海默病（AD）及相关痴呆症（ADRD）的可能性要高出1.5倍。因此，需要采取能够降低ADRD风险的干预措施。鉴于缺乏社会支持、护理责任以及维持体育活动的资源，老年拉丁裔在将体育活动（PA）纳入日常生活方面面临诸多障碍。步行和跳舞是老年拉丁裔中最常报告的两种体育活动形式，在社区场所或家中开展的室内体育活动项目可以克服参与障碍。
C.E.R.E.B.R.O.（通过锻炼改善大脑相关结果的认知增强与风险降低；英文意为“大脑”）正在测试两个远程干预项目，即BAILAMOS™舞蹈项目和¡En Forma y Fuerte!（健康与强壮！），一个体育活动/行为改变项目。参与者被随机分配到任一研究组。BAILAMOS™舞蹈项目为期6个月，参与者学习不同的拉丁舞，包括梅伦格舞、恰恰恰舞、巴恰塔舞、萨尔萨舞、昆比亚舞和基宗巴舞。训练有素的CEREBRO工作人员还会主持月度讨论。随机分配到为期3个月的¡En Forma y Fuerte!项目的人员参加柔韧性和有氧运动、力量训练以及健康教育。所有课程均通过Zoom进行直播。训练有素的研究人员协助参与者解决与技术相关的问题。在干预开始后的基线、12周和24周通过远程测试收集数据。结果包括体育活动、认知、生活质量、社会联系以及成本效益。
CEREBRO有潜力提供证据，证明提供远程干预项目以减少老年拉丁裔社区体育活动障碍的优势。
