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侧脑室巨大成熟畸胎瘤自发性破裂:一例报告

Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report.

作者信息

Xiao Yong, Liu Liang, Wang Ran, Wang Dong, Geng Liangyuan, Hu Xinhua, Liu Yong, Qian Chunfa, Zou Yuanjie

机构信息

Department of Neurosurgery, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.

出版信息

Front Oncol. 2025 Jan 27;14:1493982. doi: 10.3389/fonc.2024.1493982. eCollection 2024.

Abstract

We present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-dependent hormonal changes, which increase glandular secretion, cyst content volume, and intra-cystic pressure. The patient underwent gross total resection of the tumor, and the subsequent pathological examination confirmed the diagnosis of mature teratoma. Postoperatively, she was managed with routine follow-up without adjuvant chemotherapy or radiotherapy. During the 1-year follow-up period, the patient remained asymptomatic with no evidence of tumor recurrence. Based on this case, we recommend that gross total resection followed by close monitoring, without adjunctive chemotherapy or radiotherapy, can be an effective treatment strategy for patients with similar presentations.

摘要

我们报告一例诊断为侧脑室畸胎瘤破裂的青春期女性患者。独特的影像学和显微镜检查结果显示脑室内和蛛网膜下腔内有漂浮的油滴。畸胎瘤的自发破裂可能归因于年龄相关的激素变化,这种变化会增加腺体分泌、囊肿内容物体积和囊内压力。患者接受了肿瘤全切术,随后的病理检查证实为成熟畸胎瘤。术后,她接受常规随访,未进行辅助化疗或放疗。在1年的随访期内,患者无症状,无肿瘤复发迹象。基于此病例,我们建议对于有类似表现的患者,肿瘤全切后密切监测,不进行辅助化疗或放疗,可能是一种有效的治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99ed/11807994/2a2678583ff4/fonc-14-1493982-g001.jpg

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