Algahtani Hussein, Shirah Bader, Abdullah Ahad, Bazaid Abdulrahman
King Abdulaziz Medical City/King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
King Abdullah International Medical Research Center/King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Neurocirugia (Engl Ed). 2018 May-Jun;29(3):143-149. doi: 10.1016/j.neucir.2017.03.004. Epub 2017 May 10.
Teratoma is a common form of germ cell tumors composed of multiple tissues foreign to the site in which arise with a histological representation of all three germ cell layers. Intracranial teratomas are very rare. In this study, we report three cases of intracranial teratomas with an interesting clinical course, neuroradiology, and outcome. In addition, we review the literature and convey important messages to the neuroscience community regarding issues related to the management of these rare tumors. The present cases are interesting examples of intracranial teratoma in terms of location of the tumor and neuroimaging findings. Delay in surgical intervention may complicate the course of the disease with progressive enlargement of tumors and development of complication including hydrocephalus. Using endoscopic surgical techniques may emerge as the preferred intervention option as compared to other traditional methods. We recommend the establishment of a national and international registry for intracranial tumors.
畸胎瘤是生殖细胞肿瘤的一种常见形式，由多种与肿瘤发生部位无关的组织构成，具有所有三个胚层的组织学表现。颅内畸胎瘤非常罕见。在本研究中，我们报告了三例颅内畸胎瘤病例，其具有有趣的临床病程、神经放射学表现及转归。此外，我们回顾了文献，并就这些罕见肿瘤的管理相关问题向神经科学界传达重要信息。就肿瘤位置和神经影像学表现而言，目前这些病例是颅内畸胎瘤的有趣实例。手术干预延迟可能会使疾病病程复杂化，出现肿瘤进行性增大以及包括脑积水在内的并发症。与其他传统方法相比，使用内镜手术技术可能会成为首选的干预方式。我们建议建立一个国家和国际颅内肿瘤登记系统。
