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来自黑麦的高级卡多醇同系物(5-链烯基间苯二酚)影响红细胞膜水转运。

Higher cardol homologues (5-alkenylresorcinols) from rye affect the red cell membrane-water transport.

作者信息

Kozubek A

出版信息

Z Naturforsch C Biosci. 1985 Jan-Feb;40(1-2):80-4. doi: 10.1515/znc-1985-1-216.

DOI:10.1515/znc-1985-1-216
PMID:3993182
Abstract

The influence of 5-heptadecenylresorcinol and total rye 5-alkenylresorcinols isolated from rye grains on the red blood cell water permeability was studied using osmotic shrinkage experiments performed in 300 mM sucrose. The studied compounds induced significant increase of erythrocyte water permeability. The threshold concentration needed for the increase of water permeability was in an order of 10(-6) mol/l. The temperature dependence of the observed process showed the discontinuity which was related to the 5-alkenylresorcinol transition temperatures. It was shown also that alkenylresorcinols did not exert the biphasic action on hypotonic lysis of erythrocytes usually observed for water soluble surfactants. The specific lysine activity is postulated for the studied compounds.

摘要

利用在300 mM蔗糖中进行的渗透收缩实验,研究了从黑麦籽粒中分离出的5-十七碳烯基间苯二酚和黑麦总5-烯基间苯二酚对红细胞水渗透性的影响。所研究的化合物引起红细胞水渗透性显著增加。增加水渗透性所需的阈值浓度约为10(-6) mol/l。观察到的过程的温度依赖性显示出与5-烯基间苯二酚转变温度相关的不连续性。还表明烯基间苯二酚对红细胞低渗裂解通常不表现出水溶性表面活性剂所观察到的双相作用。推测所研究的化合物具有特定的赖氨酸活性。

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1
Higher cardol homologues (5-alkenylresorcinols) from rye affect the red cell membrane-water transport.来自黑麦的高级卡多醇同系物(5-链烯基间苯二酚)影响红细胞膜水转运。
Z Naturforsch C Biosci. 1985 Jan-Feb;40(1-2):80-4. doi: 10.1515/znc-1985-1-216.
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Haemolytic properties of cereal 5-n-alk(en)ylresorcinols.
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The effect of 5-(n-alk(en)yl)resorcinols on membranes. I. Characterization of the permeability increase induced by 5-(n-heptadecenyl)resorcinol.5-(正烷(烯)基)间苯二酚对细胞膜的作用。I. 5-(正十七碳烯基)间苯二酚引起的通透性增加的特性
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The effect of 5-(n-alk(en)yl) resorcinols from rye on membrane structure.黑麦中5-(正烷(烯)基)间苯二酚对膜结构的影响。
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[Preliminary experiments with rats on alkylresorcinols in rye].[用大鼠对黑麦中的烷基间苯二酚进行的初步实验]
Nahrung. 1981;25(9):805-10. doi: 10.1002/food.19810250902.
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Thin-layer chromatographic mapping of 5-n-alk(en)ylresorcinol homologues from cereal grains.谷物中5-n-烷(烯)基间苯二酚同系物的薄层色谱图谱分析。
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Sr-90 transfer factors for rye in podzolic soils: dependence on soil parameters.
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On measuring the diffusional water permeability of human red blood cells and ghosts by nuclear magnetic resonance.通过核磁共振测量人红细胞和血影的扩散水渗透性。
J Biochem Biophys Methods. 1990 Jul-Aug;21(2):87-102. doi: 10.1016/0165-022x(90)90057-j.
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Permeability changes of erythrocytes and liposomes by 5-(n-alk(en)yl) resorcinols from rye.
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Water transport in red blood cell membranes.红细胞膜中的水运输。
Prog Biophys Mol Biol. 1988;51(3):193-245. doi: 10.1016/0079-6107(88)90002-8.

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