Figuracion Karl Christie F, Mac Donald Christine L, Hunt David, McGranahan Tresa Michelle, Lewis Frances Marcus, Rockhill Jason, Goldberg Myron, Halasz Lia, Thompson Hilaire J
Karl Cristie F. Figuracion.
Christine L. Mac Donald.
Oncol Nurs Forum. 2024 Dec 12;52(1):51-60. doi: 10.1188/25.ONF.51-60.
To explore and describe the health outcomes and levels of environmental enrichment (EE) in participants with brain tumors after radiation therapy (RT).
SAMPLE & SETTING: 39 participants with glioma (grades 2-3) treated with RT were recruited within five years of original diagnosis from a neuro-oncology clinic.
METHODS & VARIABLES: A cross-sectional design was employed. EE measures included social connectedness, physical activity, employment, and financial stability. Health outcome measures included the Montreal Cognitive Assessment, Symbol Digit Modalities Test, global cortical atrophy rate scale, Karnofsky Performance Status Scale, and MD Anderson Symptom Inventory-Brain Tumor Module. Descriptive statistics characterized the health outcomes between participants who received photon RT and proton beam RT.
Participants who received photon RT with high EE showed higher scores on the Montreal Cognitive Assessment, Symbol Digit Modalities Test, and Karnofsky Performance Status Scale, and lower scores on the global cortical atrophy rate scale and MD Anderson Symptom Inventory-Brain Tumor Module.
EE may reduce symptom burden, promote healthy brain aging, and improve cognitive and functional status in glioma survivors receiving photon RT.
探讨并描述接受放射治疗（RT）的脑肿瘤患者的健康结局及环境丰富度（EE）水平。
从一家神经肿瘤诊所招募了39名在初次诊断后五年内接受RT治疗的2-3级胶质瘤患者。
采用横断面设计。EE测量指标包括社会联系、身体活动、就业和经济稳定性。健康结局测量指标包括蒙特利尔认知评估、符号数字模式测验、全脑皮质萎缩率量表、卡氏功能状态量表和MD安德森症状量表-脑肿瘤模块。描述性统计分析了接受光子RT和质子束RT的患者之间的健康结局。
接受高EE水平光子RT的患者在蒙特利尔认知评估、符号数字模式测验和卡氏功能状态量表上得分较高，在全脑皮质萎缩率量表和MD安德森症状量表-脑肿瘤模块上得分较低。
EE可能减轻症状负担，促进健康的脑老化，并改善接受光子RT的胶质瘤幸存者的认知和功能状态。
