Midura T F
Rev Infect Dis. 1979 Jul-Aug;1(4):652-5. doi: 10.1093/clinids/1.4.652.
Infant botulism is the newly recognized form of the disease in which illness results from the production of toxin in the infant's intestines. Between the recognition of infant botulism as a distinct clinical entity in 1976 and the end of 1978, 50 cases were identified in California. The diagnosis of botulism was established by the identification of botulinal toxin in and the isolation of Clostridium botulinum from stool specimens of the affected infants. Thirty cases were type A and 20 were type B. Fecal excretion of toxin and organisms was monitored during hospitalization and after discharge from the hospital. Stools from family members and from 160 age-matched control infants did not contain botulinal toxin. A total of 396 food and drug samples, as well as 159 environmental and miscellaneous items, were examined. None of the foods or drugs tested contained preformed toxin. However, C. botulinum organisms were isolated from the nine samples of honey, five of soil, and one of vacuum cleaner dust.
婴儿肉毒中毒是该疾病新被认识的一种形式，其病症是由婴儿肠道内产生毒素所致。在1976年婴儿肉毒中毒被确认为一种独特的临床病症至1978年底期间，加利福尼亚州共确诊了50例病例。肉毒中毒的诊断是通过在受影响婴儿的粪便标本中鉴定出肉毒毒素并分离出肉毒梭菌来确定的。其中30例为A型，20例为B型。在住院期间和出院后均对毒素和细菌的粪便排泄情况进行了监测。家庭成员以及160名年龄匹配的对照婴儿的粪便中均未含有肉毒毒素。总共检测了396份食品和药物样本以及159份环境和其他物品。所检测的食品或药物中均未含有预先形成的毒素。然而，从9份蜂蜜样本、5份土壤样本和1份吸尘器灰尘样本中分离出了肉毒梭菌。
