Ryan Jennifer M, Burke Jessica, Byrne Rachel, Capellari Emily, Harvey Adrienne, O'Connell Neil E, Omichinski Donna, Rodby-Bousquet Elisabet, Peterson Mark
CP-Life Research Centre, School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland.
Cerebral Palsy Foundation, New York, USA.
Dev Med Child Neurol. 2025 Jul;67(7):854-874. doi: 10.1111/dmcn.16254. Epub 2025 Feb 12.
To describe the prevalence and incidence of pain, identify prognostic factors for pain, determine psychometric properties of tools to assess pain, and evaluate effectiveness of interventions for reducing pain among adults with cerebral palsy (CP).
Six databases were searched to identify studies published since 1990 in any language that met eligibility criteria defined for each objective. Titles, abstracts, and full texts were screened by two independent reviewers.
Sixty-three studies were identified; 47 reporting prevalence, 28 reporting prognostic factors, four reporting psychometric properties, five evaluating intervention effectiveness. Pain prevalence ranged from 24% to 89%. Prevalence was higher among adults with CP than in adults without it. Communication function, sex, and age were prognostic factors for pain prevalence. Numerical, verbal, and pictorial rating scales were valid for assessing pain intensity in adults with CP. Pharmacological and surgical interventions had no effect on pain. An active lifestyle and sports intervention reduced pain in adults with CP compared with usual care.
Many adults with CP experience pain, although prevalence estimates vary considerably. The quality of evidence for prognostic factors and interventions is very low to low. There is a lack of evidence about effective pain management among adults with CP.
描述疼痛的患病率和发病率，确定疼痛的预后因素，评估评估疼痛工具的心理测量特性，并评估针对成年脑瘫患者减轻疼痛的干预措施的有效性。
检索六个数据库，以识别自1990年以来以任何语言发表的符合为每个目标定义的纳入标准的研究。由两名独立评审员筛选标题、摘要和全文。
共识别出63项研究；47项报告患病率，28项报告预后因素，4项报告心理测量特性，5项评估干预效果。疼痛患病率在24%至89%之间。成年脑瘫患者的患病率高于非脑瘫成年人。沟通功能、性别和年龄是疼痛患病率的预后因素。数字评分量表言语评分量表和图片评分量表在评估成年脑瘫患者的疼痛强度方面有效。药物和手术干预对疼痛无效。与常规护理相比，积极的生活方式和运动干预可减轻成年脑瘫患者的疼痛。
许多成年脑瘫患者经历疼痛，尽管患病率估计差异很大。预后因素和干预措施的证据质量非常低至低等。缺乏关于成年脑瘫患者有效疼痛管理的证据。
