Department Health and Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, 17489, Greifswald, Germany.
Department of Paediatrics, University of Lübeck, Lübeck, Germany.
Health Qual Life Outcomes. 2022 Apr 2;20(1):61. doi: 10.1186/s12955-022-01961-7.
While evidence concerning Quality of Life (QoL) in youth with cerebral palsy (CP) in comparison to the general population has been accumulating, there is a lack of studies exploring differences on a wider range of positive and negative mental health outcomes in emerging adults.
This binational case control study is part of the SPARCLE cohort study on QoL and participation of youth with CP. QoL (WHOQOL-BREF), depression (PHQ-9), anxiety (GAD-7) and self-efficacy (GSE) were assessed in 198 emerging adults with CP and 593 emerging adults from the general population, matched for country of residence, age and gender. ANCOVAs with impairment and pain as covariates were run.
Similar levels of QoL were found in both samples, except for the environmental domain, with better QoL for emerging adults with CP compared to the general population. There were significant descriptive differences regarding depression with worse levels in the CP sample, however, also worse levels of self-efficacy. Pain as a covariate had a significant negative impact on all measures, leading to poorer self-efficacy while worsening depression and anxiety; impairment had a significant worsening impact on physical QoL and self-efficacy only.
Similar expressions of mental health outcomes in emerging adults with CP and the general population indicate the high adaptive capability of emerging adults with CP.
虽然关于脑瘫青少年（CP）与普通人群的生活质量（QoL）的证据不断增加，但缺乏研究探索新兴成年人在更广泛的积极和消极心理健康结果上的差异。
这项双边病例对照研究是 SPARCLE 队列研究关于 CP 青少年的 QoL 和参与度的一部分。使用 WHOQOL-BREF 评估了 198 名 CP 青少年和 593 名来自普通人群的新兴成年人的 QoL，匹配了居住国家、年龄和性别。使用残疾和疼痛作为协变量进行了 ANCOVA 分析。
在两个样本中发现了相似的 QoL 水平，除了环境领域，CP 青少年的 QoL 优于普通人群。在抑郁方面存在显著的描述性差异，CP 样本的抑郁程度更严重，但自我效能感也更差。疼痛作为协变量对所有指标都有显著的负面影响，导致自我效能感下降，同时加重抑郁和焦虑；而残疾仅对身体 QoL 和自我效能感有显著的恶化影响。
CP 青少年和普通人群在心理健康结果上的相似表达表明 CP 青少年具有很高的适应能力。
