Department of Public Health and Epidemiology, Royal College of Surgeons in Ireland, Dublin, Ireland.
Department of Physical Therapy, Ahmadi Hospital, Kuwait Oil Company, Kuwait.
Dev Med Child Neurol. 2023 Sep;65(9):1174-1189. doi: 10.1111/dmcn.15526. Epub 2023 Feb 20.
To assess the prevalence and incidence of chronic conditions among adults with cerebral palsy (CP) and compare them to the prevalence and incidence among adults without CP.
We searched MEDLINE and Embase for studies reporting the prevalence or incidence of one or more chronic conditions among adults with CP. Two independent reviewers screened titles, abstracts, and full-text articles. Two independent reviewers extracted data relating to prevalence and incidence and appraised study quality. We performed random-effects meta-analyses to pool prevalence and incidence.
We identified 69 studies; 65 reported the prevalence of 53 conditions and 13 reported the incidence of 21 conditions. At least 20% of adults had the following conditions: depression (21%); anxiety (21%); mood affective disorders (23%); asthma (24%); hypertension (26%); epilepsy (28%); urinary incontinence (32%); malnutrition (38%); and scoliosis (46%). Adults with CP were more likely to have type 2 diabetes, anxiety, bipolar disorder, depression, schizophrenia, hypertension, ischaemic heart disease, stroke, cerebrovascular disease, asthma, liver disease, osteoarthritis, osteoporosis, underweight, and chronic kidney disease than adults without CP.
These data from 18 countries, which provide an international perspective, may be used to promote awareness, identify targets for intervention, and inform the development of appropriate supports for adults with CP.
评估脑瘫（CP）成年人中慢性疾病的患病率和发病率，并与无 CP 成年人的患病率和发病率进行比较。
我们检索了 MEDLINE 和 Embase 中报告 CP 成年人一种或多种慢性疾病患病率或发病率的研究。两位独立的审查员筛选标题、摘要和全文文章。两位独立的审查员提取与患病率和发病率相关的数据，并评估研究质量。我们进行了随机效应荟萃分析以汇总患病率和发病率。
我们确定了 69 项研究；其中 65 项报告了 53 种疾病的患病率，13 项报告了 21 种疾病的发病率。至少 20%的成年人患有以下疾病：抑郁症（21%）；焦虑症（21%）；情绪障碍（23%）；哮喘（24%）；高血压（26%）；癫痫（28%）；尿失禁（32%）；营养不良（38%）和脊柱侧凸（46%）。与无 CP 的成年人相比，CP 成年人更易患 2 型糖尿病、焦虑、双相情感障碍、抑郁症、精神分裂症、高血压、缺血性心脏病、中风、脑血管疾病、哮喘、肝病、骨关节炎、骨质疏松症、体重不足和慢性肾脏病。
这些来自 18 个国家的数据提供了国际视角，可用于提高认识、确定干预目标，并为 CP 成年人提供适当的支持。
